12. Other Picornaviral infectious diseases

Question 1

Except for foot and mouth disease in ruminants what other picornaviral diseases is important to be mentioned.

Answer 1

Swine vesicular disease in pigs

“Foot and mouth disease in pigs”

Question 2

What is important to mention about swine vesicular disease?

Answer 2

Contagious, ZOONOTIC and OIE listed

Question 3

What are the agent responsible for causing swine vesicular disease ?

Answer 3

Swine vesicular disease virus, family Picornaviridae, genus: Enterovirus

Question 4

What are susceptible hosts for swine vesicular disease?

Answer 4

Swine,
If zoonosis, human gets influenza like symptoms

Question 5

What is swine vesicular diseases causing in host?

Answer 5

Lesions (blister, vesciles) of oral mucosa membrane (blister on tongue) and foots (between hooves)

Question 6

What is transmission of swine vesicular disease?

Answer 6

• Horizontal - by rupture of skin vesicles, saliva, meat
• Fecal-oral transmission

Question 7

Clinical signs of swine vesicular disease?

Answer 7

!! Do not loose condition as in ruminants Foot and mouth disease

• Mild fever: with or without clinical signs
• Formation of vesicles on snout, lips and coronary band, interdigital space, tongue and throat
• Lameness
• Young pigs are more seriously affected but do not die

Question 8

How is swine vesicular disease diagnosed?

Answer 8

• Diagnosis and history: difficult to differentiate between other vesicular diseases
• Sample from vesicles- RT-PCR
• Serological tests- check for Ab by VNT, ELISA- check for Ab or Ag

Question 9

Treatment of swine vesicular disease

Answer 9

No treatment. Slaughter in highly infected areas! NB! 3 km protective zone.

Question 10

How is swine vesicular disease prevented?

Answer 10

• Hygiene measurements
• Cleaning and disinfection
• Treatment of meat.
• No vaccine!