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psychiatry > Neurological Basis of Psychiatric Dysfunction > Flashcards

Neurological Basis of Psychiatric Dysfunction Flashcards

1
Q

What is the primary neurotransmitter of the dorsal raphe nucleus?

A

Serotonin

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2
Q

For what brain structure is histamine the primary neurotransmitter?

A

Tuberomamillary nucleus

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3
Q

From what amino acid is serotonin derived?

A

Tryptophan

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4
Q

What monoamine neurotransmitter is most associated with chronic pain disorders and depression?

A

Norepinephrine

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5
Q

What neurotransmitter is primarily in the locus coeruleus?

A

Norepinephrine

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6
Q

From what amino acid is acetylcholine derived?

A

Serine

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7
Q

What is the metabolite of norepinephrine?

A

MHPG

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8
Q

From what amino acid is histamine derived?

A

Histidine

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9
Q

What neurotransmitter is most often implicated in sleep disorders?

A

Histamine

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10
Q

What is the neurotransmitter activity in patients with depression?

A

Decreased dopamine, serotonin, and norepinephrine

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11
Q

What monoamine neurotransmitter is most associated with depression and other mood disorders?

A

Serotonin

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12
Q

Typical antipsychotics generally target what neurotransmitter receptors?

A

Dopamine > Serotonin

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13
Q

What is the metabolite of serotonin?

A

5-HIAA

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14
Q

Dopamine is primarily an (excitatory/inhibitory) neurotransmitter.

A

Both excitatory and inhibitory depending upon the receptor

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15
Q

What is the metabolite of dopamine?

A

HVA

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16
Q

Atypical antipsychotics generally target what neurotransmitter receptors?

A

Dopamine < Serotonin

17
Q

Glutamate and GABA are the primary neurotransmitters. From what amino acids are they derived?

A

Both are derived from glutamine. GABA is derived from glutamate

18
Q

Phenylalanine derives what monoamine neurotransmitters?

A

Epinephrine, norepinephrine, dopamine

19
Q

What monoamine neurotransmitter is most often implicated in substance abuse disorders and schizophrenia?

A

Dopamine

20
Q

Dopamine is the primary neurotransmitter in what brain structure?

A

Ventral tegmental area & substantia nigra

21
Q

What is the primary neurotransmitter of the Basal Nucleus of Meynert?

A

Acetylcholine

22
Q

What is the neurotransmitter activity in patients with schizophrenia?

A

Increased dopamine and serotonin, with increased or decreased glutamate

23
Q

GABA and serotonin levels are decreased in people with anxiety disorders. What neurotransmitter level is increased?

A

Norepinephrine

24
Q

What is the primary neurotransmitter for the synaptic vesicles?

A

Glutamate & GABA

25
Q

What is the safest treatment option for a mood disorder in a pregnant woman?

A

Electroshock Therapy

psychiatry (20 decks)

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