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M&M Test 3 > B6-077 Bone Tumors > Flashcards

B6-077 Bone Tumors Flashcards

1
Q

all bone tumors derive from what cell origin?

A

osteoblasts

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2
Q

pain at night relieved by NSAIDs

A

osteoid osteoma

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3
Q

pain unresponsive to NSAIDs

A

osteoblastoma

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4
Q

benign tumor that prefers the axial skeleton

A

osteoblastoma

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5
Q

occurs in children
typically long bones
benign mass

A

osteoid osteoma

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6
Q

bimodal distribution
likes long bones and face bones

A

osteosarcoma

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7
Q

codman’s triangle

A

conventional osteosarcoma

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8
Q

treatment of osteoid osteoma

A

radiofrequency ablation

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9
Q

treatment of osteoblastoma

A

curettage or resection

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10
Q

osteosarcoma treatment

A

wide resection and chemotherapy

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11
Q

<2 cm bony mass

A

osteoid osteoma

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12
Q

> 2cm bony mass

A

osteoblastoma

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13
Q

cartilage tumors in the digits are nearly always

A

benign

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14
Q

cartilage tumors in the pelvis and axial skeleton are nearly always

A

malignant

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15
Q

lobules with reactive bone at periphery

A

enchondroma

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16
Q

chondroblasts permeate existing bone

A

chondrosarcoma

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17
Q

low-grade chondrosarcoma in the long bones is

A

atypical cartilaginous tumor

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18
Q

atypical cartilaginous tumor treatment

A

curettage

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19
Q

chondrosarcoma treatment

A

wide resection

**does not respond to chemo

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20
Q

medullary continuity

A

osteochondroma

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21
Q

lateral bony projections of growth plate
recapitulates growth plate

A

osteochondroma

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22
Q

enchondroma leaves the cortex […]

A

intact

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23
Q

fibrous dysplasia is caused by

A

congenital somatic mutation

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24
Q

is fibrous dysplasia well differentiated?

A

yes

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25
Q

streamers of bone

A

low grade central osteosarcoma

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26
Q

spicules of bone in continuity with bone

A

fibrous dysplasia

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27
Q

is low grade central osteosarcoma well differentiated?

A

no, its permeative

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28
Q

treatment of fibrous dysplasia

A

none

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29
Q

low grade central osteosarcoma treatment

A

wide resection, no chemo

30
Q

occurs in 10% of population
in children, around knee
benign, usually go away on there own

A

non-ossifying fibroma

31
Q

affects skeletally mature patients at epiphysis

A

giant cell tumor of bone

32
Q

storiform architecture
foamy histiocytes

A

non-ossifying fibroma

33
Q

huge multinucleate giant cells
nuclei of cells in stroma look like nuclei of the giant cells

A

giant cell tumor of bone

34
Q

cyst that is well demarcated and doesn’t really expand bone

A

simple bone cyst

35
Q

cyst that rapidly expands bone

A

Aneursymal Bone Cyst

36
Q

serous filled cyst

A

simple bone cyst

37
Q

blood filled cyst

A

Aneursymal Bone Cyst

38
Q

cyst that is a cellular tumor

A

Aneursymal Bone Cyst

39
Q

cyst that is an acellular tumor

A

simple bone cyst

40
Q

normal sized giant cells
spindle cells
bone spiculations

A

Aneursymal Bone Cyst

41
Q

osteomyelitis is often located in the

A

metaphysis

42
Q

small round cell tumor

A

Ewing sarcoma

43
Q

EWSR1-FLI1

A

ewing sarcoma

44
Q

normal bone with lymphocytic infiltrate

A

osteomyelitis

45
Q

giant cells
spindle cells in storiform pattern
foamy macrophages
metadiaphyseal region

A

non-ossifying fibroma

46
Q

necrotic bone
neutrophils (lymphocytic infiltate)

A

osteomyelitis

47
Q

blood circulation is richest where?

A

near growth plate

48
Q

osteomyelitis in a child is likely to present in what part of bone?

A

near growth plate

49
Q

cartilage neoplasms of the digits are likely to be

A

enchondromas

50
Q

multinucleated giant cells
stromal cells have nuclei that appear cytologically similar

A

giant cell tumor of bone

51
Q

marrow continuity

A

osteochondroma

52
Q

largely acellular (small lesion, big cyst)
mostly fibrin/fibrous walls

A

simple bone cyst

53
Q

most common benign bone tumor
typically occurs in males <25

A

osteochondroma

54
Q

benign tumor that occurs in the metaphysis of long bones

A

osteochondroma

55
Q

continuous with marrow space
covered by cartilage cap

A

osteochondroma

56
Q

.

A

.

57
Q

benign tumor that occurs in the cortex of long bones
adults <25
males > females

A

osteoid osteoma

58
Q

presents as bone pain relieved by NSAIDs
bony mass <2cm with radiolucent core

A

osteoid osteoma

59
Q

typically occurs in the vertebrae
males > females

A

osteoblastoma

60
Q

bony mass >2cm
pain unresponsive to NSAIDs

A

osteoblastoma

61
Q

typically occurs in the medulla of small bones of hand and feet
benign tumor of cartilage

A

chondroma

62
Q

benign tumor that occurs in the epiphysis of long bones (knee region)
20-40 year olds

A

giant cell tumor

63
Q

osteosarcoma typically occurs in what age range?

A

males <20 years

64
Q

malignant tumor occurring in metaphysis of long bone

A

osteosarcoma

65
Q

presents as painful enlarging mass or pathologic fracture
pleomorphic, osteoid producing cells

A

osteosarcoma

66
Q

malignant tumor more commonly occurring in adults > 50

A

chondrosarcoma

67
Q

malignant tumor that commonly occurs in the medulla of pelvis, proximal femur, and humerus

A

chondrosarcoma

68
Q

usually lytic, with intralesional calcifications, endosteal erosion, and cortex breach
malignant tumor of chondrocytes

A

chondrosarcoma

69
Q

generally occurs in patients <15 in the
diaphysis of long bones (especially femur)

A

Ewing sarcoma

70
Q

anaplastic small blue cells of mesenchymal origin

A

Ewing sarcoma

M&M Test 3 (16 decks)

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