Antiviral Flashcards

1
Q

Hepatitis associated with contaminated food/water.

Body fluids?

A

A and E
B, C+D

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2
Q

Tx for HepA

A

Rest, Adequate nutrition and fluids.

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3
Q

Tx for HepB

A

Nucleoside analogs pegylated interferon

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4
Q

Tx for HepC

A

HCV direct acting antiviral agents

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5
Q

What is GamaSTAN used to treat?

A

HAV IGg - those who don’t want the HAV.

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6
Q

What are the 2 inactivated HepA vaccines?

A

HAVRIX and VAQTA

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7
Q

What are Navi-HB and HepaGam B

A

HBV IGg

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8
Q

Heplisav-B is for which patient pop?

A

18 and older. Recombivax HB and Engerix B are for infants.

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9
Q

Not live HBV okay in pregnancy?

A

Recombivax and Engerix_B

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10
Q

HBV is treated with ______

A

NRTIs
- Adefovir, tenofovir, Entecavir, Lamivudine
Interferons
- Pegasys

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11
Q

What class of medication is tenofovir and what is it used to treat?

A

Antiviral NRTI
Tx of HBV

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12
Q

First line of Tx for chronic HBV

A

Entecavir and tenofovir and Pegasys.

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13
Q

Which HBV tx is better for patients with renal impairment?

A

Tenofovir (TAF)

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14
Q

When is Pegasys contraindicated? What class of med?

A

Pregnancy and breastfeeding
Interferon.

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15
Q

What is Pegasys contraindicated in?
Class?

A

Pregnancy and breastfeeding.
Interferon

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16
Q

HCV treatment is typically used in _____

A

Combination.

17
Q

What needs to be determined before HCV tx is selected?

A

NS5A polymorphism genotype of the virus. 1-6

18
Q

What class of med is sofosbuvir and what is it used to treat?

A

Antiviral nucleotide polymerase inhibitor.

HCV

19
Q

Hepatitis antiviral tx can. Cause

A

Hepatotxicity and nephrotoxicity.

20
Q

What are sofosbuvir, ledipasvir, Elbasvir, Grazoprevir, Velpatasvir and Ribavirinn used to treat?

A

HCV