epigenetics Flashcards

1
Q

define epigenetics

A

the study of how biology and environment signals determine gene expressions

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2
Q

what can epigenetic signals do

A

prompt changes in the number of methyl chemical groups attached to a gene, turning it on or off

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3
Q

what controls dna assessibility and gene activation or inactivation

A

den methylation and histone acetylation

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4
Q

what relaxes the dna-histone arrangement

A

acetylation

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5
Q

what binds to histone groups and unwinds the dna

A

acetyl group

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6
Q

transcription

A

rna syntheses , controls the dna

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7
Q

translation

A

protein synthesis (outside of the nucleus)

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8
Q

what is the order of gene expressions

A

dna > transcription > mRNA > translation > protein

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9
Q

what happens within the cell membrane

A

replication and transcription

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10
Q

when is it predicted that 1/3 of all americans willl be 65 years or older

A

2025

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11
Q

the most rapid population increase in the past decade has been amount people older than

A

85

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12
Q

centenarians

A

those who live to the age of 109

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13
Q

supercententarians

A

those who live to the age of 110 or more

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14
Q

who are models are successful aging

A

centenarians and supercenterarnians

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15
Q

dna methylation

A

epigenetic modification that alters how dna is read and expressed without altering the underlying sequence

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16
Q

what is referred to as the epigenetic clock

A

dna methylation

17
Q

what is the key factor in rebuilding the disappearing telomeres

A

enzyme telomerase

18
Q

both aging and age related diseases are…

A

epigenetic

19
Q

what do the formations of free radials come from

A

oxidative process , causing damage to the tissues and cells

20
Q

what is commonly referred to as our “second brain”

A

the enteric nervous system

21
Q

the enteric nervous system is a dense collection of

A

200 million to 600 million neurons in our gut

22
Q

the enteric nervous system serves as a

A

storage reservoir and production site of neurotransmitters

23
Q

studies show that individuals with chronic pain often have low

A

vitamin d

24
Q

a vitamin d3 supplement is

A

2000 IU