2nd line of defense (inflammatory response)

Question 1

causes of 2nd line defense

Answer 1

infection, mechanical damage, radiation, ischemia

Question 2

purpose of 2nd line defense

Answer 2

prevent infection of injured tissue

Question 3

when does inflammatory response occur

Answer 3

PAMPS or tissue damage

Question 4

describe inflammatory reponse

Answer 4

nonspecific, rapid, no memory cells

Question 5

vascular response

Answer 5

vasodilation; capillary permeability/leakage; WBC

Question 6

once infection in tissue what does inflammatory response do

Answer 6

Limit and control the inflammatory process
 Prevent and limit infection and further damage
 Interact with components of the adaptive immune system
 Prepare the area of injury for healing

Question 7

systems involved in inflammatory response

Answer 7

complement — antigen/antibody
clotting-fibrin mesh at site
kinin ( activate inflammatory cells)

Question 8

neutrophils

Answer 8

bacteria

Question 9

eosphils

Answer 9

parasites

Question 10

basophils

Answer 10

allergies/asthma

Question 11

recognize & eliminate cells infected
w/viruses & cancer cells

Answer 11

NK cells

Question 12

main component of adaptive immune response

Answer 12

lymphocytes

Question 13

stops bleeding & degranulation

Answer 13

platelets

Question 14

produced in bone marrow, migrate to inflammatory site
& develop into macrophages (important initiators of inflammation,
helps in wound healing, predominate in late inflammation

Answer 14

monocytes

Question 15

continuation of acute inflammation lasting 2
weeks or longer.

Answer 15

chronic inflammation

Question 16

Dysfunctional wound healing occurs as a result of
abnormalities in either inflammatory response or
reconstructive phase

Answer 16

keloid

Question 17

wound begins to heal

Answer 17

reconstruction

Question 18

he healed wound is remodeled

Answer 18

maturation