Tuberculosis Flashcards

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1
Q

What is the genus (tuberculosis)

A

Mycobacterium tuberculosis (MTB)

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2
Q

What is the type of pathogen (tuberculosis)

A

Bacteria

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3
Q

Structural features of bacteria

A

Cell wall (peptidogylcan)
Circular dna
No nucleus
Non membrane bound nucleus and organelles
Flagella
Plasmids

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4
Q

Transmission (tuberculosis)

A

Spread via cough, sneeze, spit (respiratory droplets)

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5
Q

Define infectivity

A

Ability of a pathogen to establish an infection

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6
Q

Define epidemic

A

Rapid spread of a disease in a single area or country

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7
Q

Define Pandemic

A

Rapid spread of a disease over a large area or across continents

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8
Q

Bacterial life cycle

A

Binary fission
1 DNA binds to cell membrane
2 cell undergoes DNA replication
3 cell membrane starts to pull apart, separating the strands of DNA
4 cleavage forms and cell wall is built to seperate sides
5 cell splits leaving two daughter cells

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9
Q

Tuberculosis life cycle

A

1 an uninfected possible host uptakes bacteria form infected host
2 MTB travels to alveoli, avoiding macrophages on the way
3 MTB arrives and stays in the alveoli, being surrounded by various white blood cells forming a granuloma
4 MTB complete binary fission to replicate
5 now either it will stop replicating and become dormant or keep replication and burst, releasing a lot of MTB

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