Tooth Development & Structure Flashcards

1
Q

Formation of a ball of cells, called the

A

Mourula

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2
Q

Fluid accumulates In the morula; its cells realign themselves
Formation of a fluid-filled hollow ball, called the

A

blastocyst

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3
Q

The cells on the outer later of a blastocyst are called?

A

Trophoblasts

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4
Q

The cells on the inner layer of a blastocyst are called?

A

Embryoblasts

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5
Q

The human mourla developes rapidly within days following ?

A

Fertilization

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6
Q

On day 5 of development, the human blastocyst contains what?

A
  1. Zona pelucida
  2. Trophoblast
  3. Blastoceal (yolk salk)
  4. Embryoblast
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7
Q

What is another word for the yolk sack?

A

Blastocoel

Coel=hole

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8
Q

What an egg is fertilized how long does it take to become a mourla? then a Blastocyst?

A

Moural= day 3/4
Blastocyst= 5/6

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9
Q

At day 8 after fertilization, the inner cell mass ____ differentiates into 2 groups of cells.

A

Embryoblast

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10
Q

What are the 2 groups of cells which the embryoblast layer differentites into?

A
  1. Epiblast
  2. Hypoblast
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11
Q

At the stage in which the embryoblast differentiates into the epiblast and hypoblast layer this is a a ____

A

Bilaminar embryonic disk

2 layer embryonic disk

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12
Q

In Bilaminar Germ Disk

are columnar and reorganize to form the amniotic cavity

A

Epiblasts Cells

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13
Q

The epiblast cells will reorganized itself to form the ____ and ____ linnig the amniotic cavity

A
  1. Forms embryo
  2. Forms epithelilial layering lining the amniotic cavity
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14
Q

The epiblast layer will form the entire embryo and undergoes gastrulation in week three to form the what?

A

3 germ layers

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15
Q

In Bilaminar Germ Disk

are cuboidal and form the roof of the secondary yolk sac

A

Hypoblast cells

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16
Q

In week three, the hypoblast layer is replaced by the gastrulation migrating

A

Endoderm cells

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17
Q

The hypoblast layer is considered a

A

A primitive “endoderm”

Not true; only precourssor

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18
Q

The epiblast layer is considered a what?

A

Primative ectoderm

Not true; only precoursor

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19
Q

Summary

A

Summary

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20
Q

Formation of the true germ layers
is the beginning of morphogenesis (development of body form) and is the significant event occurring during the third week.

A

Gastrulation

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21
Q

During gastrulation, the bilaminar embryonic disk is converted into a ?

A

trilaminar embryonic disk

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22
Q

development of body form

Occurs during gastrulation

A

morphogenesis

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23
Q

During gastrulation, ____ is established in the embryos

A

axial orientation

Develop head and tail orientation

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24
Q

refers to the anterior (front) aspect of the embryo

A

Ventral

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25
Q

refers to the posterior (back)

A

Dorsal

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26
Q

relating to the head

A

Cephalic

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27
Q

Relating to the tail or back of head

A

Caudal

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28
Q

is a transient embryonic anatomy structure required for patterning the surrounding tissues.

A

Notochord

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29
Q

Neuroembryological terms

are only used to describe structures within the central nervous system, above the level of the spinal cord (e.g., brainstem, cerebrum and cerebellum).

A

Roastral and Caudal

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30
Q

refers to the anterior (front) aspect of the head.

A

Rostaral

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31
Q

dorsal refer to the anterior and posterior aspects of the body, respectively.

A

Ventral (front), Dorsal (back)

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32
Q

In the brain, ventral refers to what?

A

inferior region of the brain

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33
Q

In the brain, dorsal refers to what?

A

refers to the superior region (towards the scalp).

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34
Q

Cells of the epiblast divide and migrate toward the

A

The primative streak

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35
Q

Cells of the epiblast divide and migrate toward the primitive streak.

displace and replace the hypoblast cells and become the what?

A

True embryonic endoderm

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36
Q

Cells of the epiblast divide and migrate toward the primitive streak.

they can also pack themseleves between the newly formed embryonic endoderm and epiblast to form the ?

A

Mesoderm

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37
Q

the remaining cells of the epiblast are the?

A

Ectoderm

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38
Q

Gastrulation views

A

Gastrulation Views

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39
Q

Following the for mation of the triboblastic embryo, for the next 3-4 weeks what develops?

A

Major tissue development
include the head, face, and tissues contributing to development of the teeth.

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40
Q

What layer of cells do teeth develop from?

A

Ectoderm

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41
Q

Issues of the skin, hair, pigment, neurological issue are clinical manifestions of what?

A

Issues with emrbyological developmen of the ectoderm

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42
Q

What layer?

  • Skin cells of epidermis
  • Teeth
  • Nueron of brain
  • Pigment cells
A

Ectoderm

External layer

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43
Q

What layer?

  • Cardiac muscle
  • Skeletal muscle cells
  • Tubule cell of the kidney
  • RBC
  • Smooth muscle in gut
A

Mesoderm

middle layer

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44
Q

What layer?

  • Lung cells
  • Thyroid cells
  • Pancreatic cells

Gut

A

Endoderm

interior layer

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45
Q

3 key events

What are 3 key events of the formation of the neural tube and fate of germ layers?

A
  1. Differentiation of nervous systema nd neural crest tissue from ectoderm
  2. Diferentiation of mesoderm
  3. Folding of embryo in 2 planes (rostral-caudal) & (lateraly)
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46
Q

At weeks 6-8 of embryonic development, the ____ is formed from ectoderm.

A

neuroectoderm

Eventually froms the brain

Neural tube Folding
47
Q

A group of cells separate from the neuroectoderm. These are

A

Neural Crest Cells

48
Q

Embryonic connective tissue elsewhere is derived from mesoderm and is known as

A

Mesenchyme

49
Q

**Embryonic connective tissue **in the head is derived from mesoderm and is known as

A

ectomesenchyme

“Periodontum (connective tissue) is ectomesychimally derived”

50
Q

Produced from the fusion of the neural fold beneath the surface of the ectoderm

A

Neural tube

51
Q

Anteriorly, the neural tube expands to form what 3 things?

A
  1. Forebrain
  2. Midbrain
  3. Hindbrain
52
Q

develops a series of 8 bulges (the rhombomeres)

A

Hindbrain

53
Q

The posterior neural tube developes into the?

A

Spinal cord

54
Q

A series of externally visible tissue bands
Give rise to the structures of the head and neck

A

Pharyngeal Arches

55
Q

Cranial neural crest-derived mesenchymal cells (ectomesenchyme) migrate into pharyngeal arches from midbrain and hindbrain region forming what 6 kinds of cells?

A
  1. Neurons
  2. Schwann cells
  3. Smooth muscle cells
  4. Osteoblasts
  5. Chondrocytes
  6. Odontoblast
56
Q

Cells that form teeth

A

Odontoblasts

57
Q
A
58
Q

Abnormalities in the head and face are a result of issue with ___ ___ cells in head and neck formation during embryological formation

A

neural crest cells issue

59
Q

The underdevelopment results from a Failure of the neural crest cells to migrate to the facial region.
* Drooping eyes
* Bad hair
* bad teeth
* Bad skin
* neurological defects

A

Treacher Collins syndrome

60
Q

able to develop into the tissues of the lymphatic and circulatory systems, as well as connective tissues throughout the body, such as bone and cartilage.

A

Mesenchyme

61
Q

Most of the time, mesenchyme is derived from the ____ but, in certain exceptional cases, the mesenchyme may be derived from the ____ (from neural crest cells) [ectomesenchyme].

A

Mesoderm derived = mesenchyme
Ectoderm derived from neural crest cells= ectomesencym

62
Q

Neural crest cells eventually from what in moutth?

A

Connective tissue!
* PDL
* Alevolar bone
* Dentin
etc

surface ectodern

63
Q

Enamel Formation

A

AMELOGENESIS

64
Q

Cells: ameloblasts
Ectodermal origin

A

Amelogenisis

65
Q

What cells help in enamel fromation?

A

Amenoblasts

66
Q

Dentin-Pulp complex formation

A

Dentinogenisis

67
Q

Cells: odontoblasts
Ectomesenchymal origin

A

Dentinogenisis

68
Q

What cells aid in dental pulp complex formation?

A

Odontoblasts

69
Q

Cementum formation

A

SUPPORT TISSUES FORMATION

70
Q

Cells: cementoblasts
Ectomesenchymal origin

A

Support tissue formation (cementum)

71
Q

What cells aid in cemenetum formation?

A

cementoblasts

72
Q

What are the 3 overlapping phases of tooth development?

A
  1. Inititation (est. site of future teeth)
  2. Morphogenisis (det shape of tooth)
  3. Histogenisis (fully formed dental tissue via cell differentiation)
73
Q

What stage of tooth dev?

Establish sites of future teeth.

A

Initiation

74
Q

What stage of tooth dev?

Determine shape of tooth.

A

Morphogenisis

75
Q

What stage of tooth dev?

Fully formed dental tissues via cell differentiation.

Amenoblast, cementoblast, odontoblast start to develop

A

Histogenisis

76
Q

During inital embryological development there are designated areas for both __ and ___.

A

Primary and permanent teeth.
All teeth are pre-formed. (primary 1st, secondary later)
why mothers health during pregnancy affects in child

77
Q

What are the 3 stages of tooth formation?

A
  • Bud
  • Cap
  • Bell
78
Q

Inward growth onto the underlying ectomesenchyme the on each thickened epithelial shelves

Signals beggining of tooth development

A

Dental Lamina

S

79
Q

The ____ thickens into dental lamina, and ectomesencyme cells migrate around it

Primary epithelial band

A

Outer epithelium thickens to from dental lamina.

80
Q

Explain A and B

A

Dental lamina (B)- lingually located
Vestibular lamina (A)- buccally located

thickening of dental OE itno dental lamina singals tooth development initiation

81
Q

are embryonic structures that give rise to structures such as hair follicles and teeth

form along dental lamina, signal where bud will form

A

Dental Placode

82
Q

Condensation!
first epithelial incursion into the ectomesenchyme of the jaw.
Cells show little change in shape or function.

A

Bud stage

Tooth grows inward into jaw, mesenchyme cells migrate toward bud

83
Q

Bud stage, explain A and B

A

A= enamel organ; dental lamina
B= (ecto)mesenchymal condensation

84
Q

During the bud stage is there differentiated cells?

A

NO! only group of condensed cells. Differentiation is in cap stage!

85
Q

Marks the onset of morphologic differences between tooth germs that give rise to different types of teeth.

A

Bud-to-Cap transition

86
Q

Explain

Cap Stage

A

Cap Shaped; developing tooth, contain enamel organ, cervical loop transition from inner and outer enamel epithelium.

Cervical loop grow and trap dentin

Inner= dentin

Closer to middle= pulp tissue of teeth

87
Q

is a cellular aggregation seen in a developing tooth and it lies above the dental papilla.

A

Enamel Organ

88
Q

At the periphery of the enamel organ, the cells assume a low cuboidal shape and form the

A

Outer Enamel Epithelium

89
Q

The cells bordering on the dental papilla assume a short columnar shape and are characterized by high glycogen content

A

Inner enamel Epithelium

90
Q

center of the enamel organ

A

Stellate reticulum

91
Q

In the bell stage, some epithelial cells between the inner enamel epithelium and the stellate reticulum differentiate into a layer called the

A

Stratum Intermedium

92
Q

region where the inner and outer enamel epithelia meet at the rim of the enamel organ is known as the

A

Cervical loop; roots

93
Q

ball of condensed ectomesenchymal cells which will eventually form the dentin and the pulp of the tooth.

A

Dental papilla

94
Q

The condensed ectomesenchymelimiting the dental papilla and encapsulating the enamel organ

gives rise to the supporting tissues of the tooth

A

Dental follicle

95
Q

The
* enamel organ
* dental papilla, and
* dental follicle together constitute the?

A

Tooth germ (dental organ)

96
Q

tologic slide showing a tooth bud.
What is A B C?

A
  • A: enamel organ
  • B: dental papilla
  • C: dental follicle
97
Q

What does this slide display?

A

Early cap stage of tooth development (arrows).
A = Meckel’s cartilage;
B = developing tongue

98
Q

early cap

What does the cap stage start with?

A

cellular differentiation within the enamel organ.

99
Q

early cap

During histodifferentiation in the cap stage, central cells in the enamel organ form the?

A

Stellate Reticulum

100
Q

early cap

During histodifferentiation in the cap stage, epithelial cells differentiate into what 2 kinds of cells?

A

inner and outer enamel epithelia.

101
Q

During the late cap stage what 5 things have formed?

A
  • A = stellate reticulum
  • B = outer enamel epithelium
  • C = inner enamel epithelium;
  • D = dental papilla;
  • E = dental follicle (everything around cap; future pdl)
102
Q

By the bell stage is the tooth type decided?

A

Yes!

103
Q

During this stage, the cells that will be making the hard tissues of the crown (ameloblasts and odontoblasts) acquire their distinctive phenotype (histodifferentiation), and the crown completes its morphodifferentiation and attains its full size.

A

Bell Stage

104
Q

Early bell

What is A and B?

A

A = inner investing layer of dental follicle;
B = outer layer of dental follicle

105
Q

During the early bell stage what does the dental papilla look like in comparatison to how it was in the cap stage?

A

Dental Papilla is more invaginated and condensed

106
Q

Early Bell

What tooth class will this be?

A

Incisor

107
Q

is a permanent tooth that replaces a primary (deciduous) tooth.

A

succedaneous teeth

108
Q

Permanent Incisors, Canines, and Premolars are what type of dentition?

A

succedaneous teeth

Note tooth bud of permanent tooth forming

109
Q

What is the only class of permanent dentition that are not succedaneous?

A

Molars! They are brand new.

110
Q

What stage of tooth dev?

Formation of buds on mandible and maxilla

A

Initiation

111
Q

When permanent molars form do they have teeth around them? Why?

A

No! because they are not succedaneous. Form alone

112
Q

Explain why primary teeth roots bend buccally.

A

In development,** primary tooth bud is buccal** and permanent tooth bud is lingual.

113
Q

Review Stages of tooth Dev.

A