AKI and ICU Neph Flashcards

1
Q

Which ONE of the following is the BEST marker of renal recovery in AKI-D?
A. Urine output
B. BUN
C. Creatinine
D. Overall Clinical statis

A

A. Urine output

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2
Q

What are causes of osmotic nephropathy? (5)

A
  1. IVIG sucrose
  2. Hydroxyethyl starch
  3. Dextran
  4. Mannitol
  5. Radiocontrast agents
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3
Q

What is the definition of intraabdominal hypertension?

A

IAP > 12

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4
Q

What is the definition of intraabdominal compartment syndrome?

A

IAP > 20

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5
Q

What is the formula for abdominal perfusion pressure, and what is the normal value?

A

APP = MAP - IAP;
NL is > 50

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6
Q

What are the differentials for AKI in liver disease?

A
  1. Hepatorenal syndrome
  2. Prerenal azotemia (volume depletion)
  3. ATN
  4. AIN
  5. Glomerular dse: IgAN, cryoglobulinemia, MPGN, membranous nephropathy
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7
Q

What is normal access pressure in dialysis?

A

NL: -50 to -150 mmHg

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8
Q

A very positive access pressure indicates? (3)

A
  1. Kinks
  2. Occlusion of venous return pump
  3. Erroneous placement in arterial circulation
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9
Q

A very negative access pressure indicates?

A

Access problem (kink, clot, malposition, very low circulatory volume)

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10
Q

What is normal filter pressure?

A

50-250 mmHg

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11
Q

What does a high filter pressure indicate?

A

Clogging of membrane or downstream clotting

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12
Q

How do you calculate transmembrane pressure (TMP)?

A

TMP = mean filter pressure - effluent pressure

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13
Q

A high TMP (>150 mmHg) indicates?

A

clogging of the filter (e.g. protein buildup) esp in high inflammatory states

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14
Q

How do you calculate pressure drop?

A

Pressure drop = prefilter pressure - return pressure

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15
Q

A high pressure drop (>150 mmHg) indicates?

A

Filter clotting (eg blood clots in the hollow fibers)

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16
Q

What is the relationship between filtration fraction and blood flow rate? Directly or inversely proportional?

A

Inversely proportional
Therefore, to decrease FF, one must increase the Qb