Traumatic brain injury Flashcards

1
Q

What is traumatic brain injury?

A

Acquired disruption of the normal function or structure of the brain caused by.a head impact or external force

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2
Q

What type of trauma can cause traumatic brain injuries?

A
  • Blunt trauma
  • Penetrating injuries
  • Blast injuries
  • However not all impacts to the head cause TBI
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3
Q

According to the WHO how do you classify mild TBI?

A

Mild TBI is due to a blunt or mechanical force that results in some type of transient confusion, disorientation, or loss of consciousness lasting not more than 30 minutes; is possibly associated with transient neurobehavioural deficits; and has a Glascow Coma Scale (GCS) score no lower than 13.

some pts may intially present with none of these

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4
Q

How do you classify TBI based on GCS?

A

Mild TBI: GCS 13-15; mortality 0.1%
Moderate TBI: GCS 9-12; mortality 10%
Severe TBI: GCS <9; mortality 40%.

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5
Q

How do you classify TBI based on mechanism?

A
  • Blunt TBI: external mechanical force leads to rapid acceleration or deceleration with brain impact. Blunt TBI is typically found in the setting of motor vehicle-related injury, falls, crush injuries, or physical altercations.
  • Penetrating TBI: occurs when an object pierces the skull and breaches the dura mater, seen commonly in gunshot and stab wounds.
  • Blast TBI: commonly occurs after bombings and warfare, due to a combination of contact and inertial forces, overpressure, and acoustic waves
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6
Q

How do you classify TBI by area of brain involvement

A
  • Diffuse brain injury includes diffuse axonal injury (DAI), hypoxic brain injury, diffuse cerebral oedema, or diffuse vascular injury.
  • Focal injury includes specific lesions such as contusions, intracranial haematomas, infarctions, axonal tears, cranial nerve avulsions, and skull fractures.

both types often co-exist

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7
Q

What is primary injury in TBI?

what are some examples

A
  • Due to the immediate mechanical force
  • May incl the following
    Concussion
    Skull fracture
    Contusion (localised punctate haemorrhages)
    Haematoma: Subdural, epidural, intracerebral
    Subarachnoid haemorrhage
    Axonal shear or laceration
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8
Q

What is secondary injury in TBI?

A
  • Evolving pathphysiological consequences of the primary injury
  • May incl the following:
    Cerebral oedema
    Increased intracranial pressure
    Haemorrhage progression
    Seizures
    Ischaemia
    Infection
    Traumatic venous sinus thrombosis.
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9
Q

What are the symptoms of concussion?

A
  • short-lived confusion
  • disorientation
  • loss of consciousness, with or without neurobehavioural deficits.
  • headache
  • vestibular deficit
  • Occur in most pts with TBI, typically the only findings in pts with mild TBH
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10
Q

What is post concussive syndrome?

A

the presence of 3 or more of the following symptoms after a head injury:
* headache,
* dizziness,
* fatigue,
* irritability,
* difficulty with concentrating and performing mental tasks, i
* mpairment of memory,
* insomnia
* reduced tolerance to stress, emotional excitement, or alcohol

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11
Q

When do you CT for a ?TBI?

Adults

A

For people 16 and over who have sustained a head injury, do a CT head scan within 1 hour of any of these risk factors being identified:

  • a GCS score of 12 or less on initial assessment in the emergency department
  • a GCS score of less than 15 at 2 hours after the injury on assessment in the emergency department
  • suspected open or depressed skull fracture
  • any sign of basal skull fracture (haemotympanum, ‘panda’ eyes, cerebrospinal fluid leakage from the ear or nose, Battle’s sign)
  • post-traumatic seizure
  • focal neurological deficit
  • more than 1 episode of vomiting

For people 16 and over who have had some loss of consciousness or amnesia since the injury, do a CT head scan within 8 hours of the head injury, or within the hour in someone presenting more than 8 hours after the injury, if they have any of these risk factors:

  • age 65 or over
  • any current bleeding or clotting disorders
  • dangerous mechanism of injury (a pedestrian or cyclist struck by a motor vehicle, an occupant ejected from a motor vehicle or a fall from a height of more than 1 m or 5 stairs)
  • more than 30 minutes’ retrograde amnesia of events immediately before the head injury.

https://www.nice.org.uk/guidance/ng232/chapter/Recommendations#investigating-clinically-important-traumatic-brain-injuries

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12
Q

When do you CT for a ?TBI?

Child

A

For people under 16 who have sustained a head injury, do a CT head scan within 1 hour of any of these risk factors being identified:
* suspicion of non-accidental injury

  • post-traumatic seizure
  • on initial emergency department assessment, a GCS score of less than 14 or, for babies under 1 year, a GCS score (paediatric) of less than 15
  • at 2 hours after the injury, a GCS score of less than 15
  • suspected open or depressed skull fracture, or tense fontanelle
  • any sign of basal skull fracture (haemotympanum, ‘panda’ eyes, cerebrospinal fluid leakage from the ear or nose, Battle’s sign)
  • focal neurological deficit
  • for babies under 1 year, a bruise, swelling or laceration of more than 5 cm on the head.

For people under 16 who have sustained a head injury and have more than 1 of these risk factors, do a CT head scan within 1 hour of the risk factors being identified:
*

  • loss of consciousness lasting more than 5 minutes (witnessed)
  • abnormal drowsiness
  • 3 or more discrete episodes of vomiting
  • dangerous mechanism of injury (high-speed road traffic accident as a pedestrian, cyclist or vehicle occupant, fall from a height of more than 3 m, high-speed injury from a projectile or other object)
  • amnesia (anterograde or retrograde) lasting more than 5 minutes (it will not be possible to assess amnesia in children who are preverbal and is unlikely to be possible in children under 5)
  • any current bleeding or clotting disorder.
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13
Q

How may an extradural haemorrhage present?

A
  • may or may not have a lucid interval
  • Reduced GCS
  • Headache
  • Cranial N. III–> Blown
  • Coning–> Cushings Triad (HTN, bradycardia and irregular breathing- in that order)
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14
Q

How do you manage Extradural haemorrhage?

A
  • Definitive treatment: SURGERY
  • Mannitol/ 5% hypertonic saline–> reduces cerebral pressure–> reduces swelling. Need catheter to keep bladder empty
  • Position pt to 30/40 degrees to encourage venous drainage
  • Keep all obs normal, CO2 at the lower end of normal
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15
Q

Subdural haemorrhage risk factors?

A

Old age
coagulopathy/ anticoag use
alcholism

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16
Q

Symptoms of subdural haemorrhage?

A
  • Fluctuating confusion/ consciousness
  • headache
  • N&V
  • Diminised eye/verbal/motor response
17
Q

Subdural vs Extradural on head CT?

A

EXTRADURAL: bi-convex
SUBDURAL: Crescent shape

18
Q

Subarachoid haemorrhage features?

A
  • Sudden occipital headache
  • Usually spontaneous due to ruptured berry aneurysm but also due to trauma
  • N&V
  • Meningism
  • Coma
  • Seizures
19
Q

Inv for SAH?

A
  • non-contrast head CT- acute blood (hyperdense)- in the basal cisterns, sulci and maybe ventricles
  • If CT head is done within 6 hours of symptom onset and is normal
    new guidelines suggest not doing a lumbar puncture: consider an alternative diagnosis
  • if CT head is done more than 6 hours after symptom onset and is normal: do a lumber puncture (LP)
  • timing wise the LP should be performed at least 12 hours following the onset of symptoms to allow the development of xanthochromia (the result of red blood cell breakdown).
  • xanthochromia helps to distinguish true SAH from a ‘traumatic tap’ (blood introduced by the LP procedure).
  • as well as xanthochromia, CSF findings consistent with subarachnoid haemorrhage include a normal or raised opening pressure
  • if the CT shows evidence of a SAH
    referral to neurosurgery to be made as soon as SAH is confirmed
20
Q

What is intracerebral haemorrhage?

A

Collection of blood within the substance of the brain

21
Q

Causes/ RFs of intracerebral haemorrhage?

A
  • hypertension
  • vascular lesion (e.g. aneurysm or arteriovenous malformation)
  • cerebral amyloid angiopathy
  • trauma
  • brain tumour
  • infarct (particularly in stroke patients undergoing thrombolysis).
22
Q

What will CT head of intracerebral haemorrhage show?

A
  • hyperdensity within the substance of the brain
23
Q

T

Treatment of intracerebral haemorrhage?

A
  • conservative under the care of the stroke physicians
  • large clots in patients with impaired consciousness may warrant surgical evacuation
24
Q

How does someone with a diffuse axonal injury present?

A
  • altered mental status or coma
  • physical exam findings disproportionate to the CT findings
25
Q

CT findings in Diffuse axonal injury?

A
  • oedema and petechial haemorrhages at the grey/ white junction within the corpus callosum and the brainstem