ANP and BNP basics Flashcards
what is ANP
atrial natriuretic peptide
why is the hormone ANP released by the heart cells
due to atrial wall stretching
what is BNP
brain natriuretic peptide
why is BNP hormone released by heart cells
due to ventricle wall stretching
what do the hormones BNP and ANP work against
angiotensin 2, aldosterone, ADH and renin
what do NPs do
directly dilate veins and arteries
when NPs increase venous compliance by vein dilation what does it decrease
decrease central venous pressure which
reduces cardiac output by
decreasing ventricular preload
when NPs dilate arteries what does it decrease
systemic vascular resistance and systemic arterial
pressure
how do NPs affect kidneys
increasing glomerular filtration rate (GFR)
and filtration fraction
when NPs increase GFR what does it produce
natriuresis (sodium excretion) and diuresis (fluid excretion)
A second renal action of NPs is that they decrease ____ and _____ and lead to _____
renin release thereby decreasing circulating levels of angiotensin II and
aldosterone. and leads to further diuresis and natriuresis
NPs are a counter regulatory system for ______ system
RAAS system
