Lungs - A1 Flashcards

1
Q

What is the path that air takes when travelling to the lungs?

A

Air travels down the trachea -> bronchi -> bronchioles -> alveoli

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2
Q

What does the trachea have that provides structure and support?

A

The trachea has rings of cartilage which help to prevent the trachea from collapsing in on itself.

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3
Q

What are the alveolus and what is their purpose?

A

The alveolus are mini air sacs that are used as a gas exchange surface.

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4
Q

What are the alveolus lined with?

A

The alveolus are lined with epithelium (outermost layer) which are one cell thick.

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5
Q

What are endothelium cells?

A

Line the inside of a cell.

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6
Q

What are the alveolus covered in?

A

A network of capillaries.

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7
Q

Approximately how many alveoli are in each lung and what is the benefit of this?

A

There are approx. 350 million in each lung and they provide a large surface area for gas exchange.

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8
Q

What is the trachea?

A

A wide tube that carries air to the bronchus.

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9
Q

What is the effect of cartilage on the trachea?

A

There are about 20 rings of hard cartilage that keep the air passage open due to pressure changes. The rings are C-shaped, separated by muscle and elastic tissue. The soft tissue allows the trachea to be flexible and to stretch.

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10
Q

What are the bronchus?

A

The bronchus(2 bronchioles) are the first branch off the trachea and allows passage of air into the bronchioles.

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11
Q

What else do the bronchus have that is similar to the trachea?

A

They also have cartilage in their walls to keep them open.

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12
Q

What are the bronchioles?

A

They’re smaller branches of the bronchus and end in clusters of alveoli. The smaller bronchioles have only muscle and elastic fibres so that they can contract and relax easily during ventilation.

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13
Q

What type of cells need the most ATP?

A

Active muscle cells, cells producing useful substances(e.g. hormones or enzymes) and brain cells.

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14
Q

What does ventilation consist of?

A
  • inspiration and expiration
    -Controlled movements of the diaphragm, internal and external intercostal muscles
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15
Q

What is the thoracic cavity?

A

The area where the lungs sit.

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16
Q

Describe the process of inspiration.

A
  • The diaphragm contracts and flattens, and the external intercostal muscles contract and move the ribcage upwards and outwards - increasing the volume of the thoracic cavity.
    -This increase in volume decreases the pressure in the thoracic cavity to below atmospheric pressure.
    -This causes air to flow into the lungs from an area of high to low pressure down a pressure gradient.
17
Q

Describe the process of expiration.

A

-The diaphragm relaxes and domes upwards, and the external intercostal muscles relax and cause the ribcage to move downwards and inwards.
-This decreases the volume of the thoracic cavity, which increases the pressure to above atmospheric pressure.
-air is then forced down a pressure gradient and out of the lungs.

18
Q

What is forced expiration?

A

-Expiration can be forced, for example when blowing out a candle
-During forced expiration, external intercostal muscles relax(as before) and internal intercostal muscles contract.
-This causes the ribcage to be pulled in and down further
-The two sets of intercostal muscles are antagonistic(opposite).

19
Q

What does Fick’s Law state?

A

The rate of diffusion is directly proportional to the surface area multiplied by the concentration gradient, divided by the diffusion distance.

20
Q

What are three things all gas exchange surfaces have?

A

Large surface area, large concentration gradient, short diffusion distance.

21
Q

What features must gas exchange sites(alveoli) have?

A

-Moist
-Thin - the alveolar epithelium is only 1 cell thick. This means that there is a short diffusion pathway, which speeds up diffusion.
-Permeable.
-Have a large surface area - millions of alveoli, meaning there’s a large S.A. for diffusion/gas exchange.
-Good blood supply(also ventilation) - maintains a steep concentration gradient of oxygen and carbon dioxide between the alveoli and the capillaries.

22
Q

What happens to oxygen in the alveolus?

A

Oxygen diffuses down a concentration gradient through the alveolus epithelium and then through the capillary endothelium, and then binds to haemoglobin.

23
Q

What are the measures of lung function?

A

Tidal volume, ventilation rate, forced expiratory volume1 , forced vital capacity1

24
Q

What is tidal volume?

A

The volume of air in each breath - 0.4 dm(cubed) and 0.5dm(cubed) for adults.

25
Q

What is ventilation rate?

A

The number of breaths per minute - usually around 15 (for adults).

26
Q

What is forced expiratory volume1 ?

A

The maximum volume of air that can be breathed out in 1 second.

27
Q

What is forced vital capacity1 ?

A

The maximum volume of air it is possible to breathe forcefully out of the lungs after a deep breath.

28
Q

What is pulmonary ventilation?

A

The volume of air breathed in per minute.

29
Q

What is the equation for pulmonary ventilation?

A

Pulmonary ventilation = ventilation rate X tidal volume

30
Q

What would happen to the numbers in the pulmonary ventilation equation during exercise?

A

They would increase.

31
Q

What happens when there is a reduced rate of gas exchange in alveoli?

A

-Less oxygen can diffuse into the bloodstream
-Body cells receive less oxygen so rate of aerobic respiration decreases.
-Less energy released so sufferers feel tired and weak.