Adaptive Immunity -3

Question 1

B cell progenitors’: contact with bone morrow

Answer 1

Pro B cells

Question 2

Il-7 necessary at this early developmental stage.

Answer 2

Pro B cells

Question 3

Rearrangement of genes

Answer 3

Pro B cells

Question 4

Markers that include surface antigens

Answer 4

CD19
CD45
CD43
CD24
C-kit
Tdt
Rag -1
Rag -2

Question 5

Chromosome involve in rearrangement of genes

Answer 5

Chromosome 14

Question 6

Cd that is always present in every phase

Answer 6

CD19

Question 7

1st heavy chain synthesized al the new chains
Igm- immunoglobulin

Answer 7

Pre B sells

Question 8

2 heavy chains and surrogate light chain

Answer 8

Pre B cell

Question 9

Elimination of B cells that become self reactive receptors

Answer 9

Immature B cells

Question 10

Major histo compatibility complex MHC

class ii molecules

Answer 10

CD21, 40

Question 11

What Cd is important in the interaction of 3 cells within T cells

Answer 11

Cd 40

Question 12

Receptor for breakdown product of component C3.

Answer 12

CD21

Question 13

Remain in the spleen

Answer 13

Marginal B cells

Question 14

Migrate to lymph nodes

Answer 14

Follicular B cells

Question 15

Proteins on the surface of mature B cells

Answer 15

Cd 19
cd 21
Cd 81
Cd 225
Cd 19 complex

Question 16

Presence of CD25 and IL -2

Answer 16

Activated B cells

Question 17

Transform into a blast will give rise to both plasma cell and memory cell

Answer 17

Activated B cell

Question 18

Antibody production

Answer 18

Plasma cells

Question 19

Spherical or ellipsoial cells between 10 and 20 nm

Little no surface immunoglobulin

Answer 19

Plasma cells

Question 20

Located in germinal centers in the peripheral lymphoid organ

Answer 20

Plasma cells

Question 21

T or F

in bone marrow, plasma cells can curare in niches around by stromal cells

Answer 21

True

Question 22

T or F

Plasma cells, found elsewhere are non dwiding and after several days of antibody production they die without proliferation

Answer 22

TRUE

Question 23

Responsible for the memory for the adaptive immunity

Answer 23

Memory cells

Question 24

Cell to cell contact

Answer 24

T-lymphocytes

Question 25

Responsible for cellular immune responses and are involved in the regulation of antibody reactions in conjunction with B lymphocytes

Answer 25

T lymphocytes

Question 26

Early surface markers

Answer 26

Tells include CD44 and CD25