mitosis/meiosis Flashcards

1
Q

what is mitosis?

A

cell division which occurs in eukaryotic organisms. in which the maternal cell divides to form 2 genetically identical daughter cells. allows replacement, growth, repair of lost cells and so on…

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2
Q

mitosis passes through 6 phases what are these?

A
  • interphase
  • prophase
    -> prometaphase
  • metaphase
  • anaphase
  • telophase
  • cytokinesis
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3
Q

what is interphase

A

cell going about its normal business
G1 -
S DNA is duplicated (synthesised) during this phase
G2

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4
Q

what is prophase

A

DNA condenses to become chromosomes which are visible under a microscope. centrioles move to opposite ends of the cell and extend microtubules out. (mitotic spindle) the centromeres at the centre of the chromosomes also begin to extend fibres outwards

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5
Q

prometaphase?

A
  • nuclear membrane disappears, microtubules attach centrioles to centromeres and start pulling the chromosomes
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6
Q

metaphase?

A

chromosome becomes aligned in the middle of the cell

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7
Q

anaphase?

A

chromosome pairs split (centromeres) are cut and one of each pair (sister chromatids) move to either end of the cell

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8
Q

telophase

A

sister chromatids reach opp ends of the cell and become less condensed and no longer visible, new membranes form around the new nuclei for the daughter cells

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9
Q

cytokinesis

A

an actin ring around the centre of the cell shrinks and splits the cell in two

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10
Q

interphase

A

cell going about normal daily business
preparing for and doubling its DNA to form pairs of chromosomes

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11
Q

if there is an error in mitotic division what can that mean for new daughter cell?

A
  • the error will be carried on to that cell
  • an error in one cell can go on and be a error in a huge no of cells. chromosomal damage e.g. trisomy 21 -> down syndrome
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12
Q

what happens during meiosis?

A
  • a single cell divides twice to form 4 new cell
  • these cells have half the normal no of chromosomes (haploid)
  • method of producing spermatozoa and oocytes
  • when an egg is fertilised by a sperm the chromosomes will combine to form a cell with the normal no of chromosomes
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13
Q

meosis I?

A

first division of meosis
during meosis I a cell passes through phases v similar to those of mitosis but w significant differences - but w some significant differences

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14
Q

at the end of meosis I how many chromosomes does each cell have?

A

23 chromosomes and each chromosome has 2 chromatids (haploid)

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15
Q

what is the key event of meosis I?

A

separation of homologous chromosomes, rather than the separation of sister chromatids as occurs during mitosis.

also in meosis I prophase I stage there is homologous recombination whereby the homologous chromosomes exchange DNA

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16
Q

what are homologous chromatids?

A

two chromosomes that make up the pair of chromosomes that we talk about in diploid cells
they are described as containing genes for the same biological features however the genes may be slightly different

17
Q

female sex hormones are homologous but the male sex chromosomes are not true or false

A

true

18
Q

does DNA replicate from meosis I to meosis II?

A

no it does not. therefore there is no interphase therefore they are 2 haploid cells to begin with

19
Q

anaphase in meosis II

A

chromosome pairs are split (centromeres cut) one of each pair (sister chromatids) moving to either end of the cell (haploid)