Infertility Flashcards

1
Q

How to be diagnosed infertile

A

1 year of trying, <35 y/o
6 months of trying, >35y/o

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2
Q

Infertility affects:

A

1 in 6 couples (Canada)

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3
Q

Impacts of diagnosis

A

Social, economic, physical, financial, psychological

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4
Q

Infertility factors percentage

A

women: 40%, men: 30%, combined: 20%, unexplained: 10%

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5
Q

Risk factors for women

A

overweight, hormonal imbalances, endometriosis, eating disorders, >27 y/o, uterine fibroids, psychological stress, and more

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6
Q

Risk factors for men

A

substance use (smoking, marijuana), BMI, heavy alcohol consumption, STIs, cryptorchidism (undescended testes), and more

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7
Q

IVF

A

in vitro fertilization

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8
Q

Clomiphene citrate (clomid)

A

Non-steroid synthetic anti estrogen, induces ovulation, discontinue after 3 cycles of use.
Nurse advise couple to have intercourse every other day for 1 week after day 5 of medication

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9
Q

highest rate of pregnancy

A

6 days leading up to and including day 1 of ovulation

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10
Q

initial screening for males

A

reproductive history and semen analysis

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11
Q

clomiphene citrate test

A

tests for ability of eggs to be fertilized

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12
Q

home ovulation predictor kits

A

tests for amount of LH present in urine–>high level of LH/surge from baseline=most fertile day

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13
Q

hysterosalpingography

A

test for obstruction of fallopian tube, dye is inserted, check to see if fallopian tubes are patent

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14
Q

laparoscopy

A

check for my physical ailments of uterus and etc.

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15
Q

path of egg (ovum)

A

released from ovary than goes to fallopian tube and then goes down

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16
Q

process of healthy reproduction

A

ovum is released from ovum than travels down fallopian tuba and continues down, sperm enters the vagina and swims to meet eh ovum at the outermost of fallopian tube–>fertilization takes place here

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17
Q

duration of pregnancy

A

40 weeks from fertilization

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18
Q

3 stages of fetal development

A

pre embryonic stage, embryonic stage, fetal stage

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19
Q

pre embryonic stage

A

fertilization through the second week

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20
Q

embryonic stage

A

end of the second week through the eighth week

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21
Q

fetal stage

A

end of the eighth week until birth

22
Q

zona pellucida

A

clear protein layer, blocks all sperm except for one, disappears in about 5 days

23
Q

gametogenesis

A

formation of gametes (sex cells) by meiosis

24
Q

spermatogenesis

A

one spermatogonium gives 4 sperm

25
Q

oogenesis

A

from oogonium–>one mature ovum and the rest are polar bodies (3)

26
Q

three embryonic layers of cell

A

endoderm, mesoderm, ectoderm

27
Q

endoderm

A

respiratory, liver, digestive, pancreas

28
Q

ectoderm

A

CNS, special sense, skin, glands

29
Q

mesoderm

A

skeletal, urinary, circulatory, reproductive organs

30
Q

where does fertilization take place

A

ampulla of fallopian tube

31
Q

what is a zygote

A

union of sperm and ovum, 46 chromosomes

32
Q

which determines the sex of the baby

A

sperm

33
Q

morula

A

mass/cluster of 16 cells, from 4 cleavages

34
Q

blastocyst

A

hollow ball of cells will become embryo and amnion (amniotic fluid)

35
Q

trophoblast

A

form placenta and chorion

36
Q

when does implantation occur

A

7-10 days after fertilization/conception in endometrium

37
Q

where on the uterus does implantation happen

A

fundus, thickest, rich with blood flow–>allows placenta not to implant too “much”

38
Q

chorion

A

outer membrane of fluid-filled sac, amniotic sac

39
Q

amnion

A

inner layer of amniotic sac

40
Q

what is amniotic fluid made up of

A

fetal urine, fluid transported from the maternal blood

41
Q

what does amniotic fluid do

A

help maintain constant body temp, help with symmetric growth, cushion the fetus, helps the umbilical cord not be compressed

42
Q

hCG

A

preserves the corpus lutecium and progesterone production, endometrial lining is preserved

43
Q

estrogen

A

enlargement of breasts, uterus and external genitalia

44
Q

progesterone

A

maintains the endometrium, situates metabolism and breast development

45
Q

relaxin

A

acts synergistically with progesterone to maintain pregnancy, causes relation of pelvic ligaments, softens cervix to prep for birth

46
Q

ductus venosus

A

connects umbilical vein to the inferior vena cava

47
Q

ductus arteriosus

A

connects the main pulmonary artery to the aorta

48
Q

oligiohyrdaminos

A

not enough amniotic fluid <500mL, issues with movement, skeletal, muscular development

49
Q

polyhydroaminos

A

too much amniotic fluid >2000mL, neural tube defects, maternal diabetes, etc.

50
Q

foramen ovale

A

anatomic opening between left and right atrium of heart

51
Q

fetal circulation

A

umbilical vein carries oxygenated blood from placenta to liver (through ductus venosus)–>then carried to inferior vena cava (RIGHT atrium of heart). Some of the blood is shunted through the foramen ovale to left side of heart. remaining blood is shunted through ductus arteriosus arterioles into the aorta to supply the rest of the body

52
Q
A