Exqm 2 Ch 5-8

Question 1

Enzyme that controls level of ACh by breaking it down into choline and acetic acid

Answer 1

Acetylcholinesterase (AChE)

Question 2

Group of neurotransmitters and hormones characterized by two chemical similarities: a core structure of catechol and nitrogen-containing amine. They belong to a wider group of transmitters called monoamines or biochemical amines

Answer 2

Catecholamines

Question 3

Which NTs are catecholamines ?

Answer 3

Dopamine, norepinephrine

Question 4

Refers to a compound or transmitter that contains a single amine group (-NH2)

Answer 4

Monoamines

Question 5

Enzyme responsible for metabolic breakdown of catecholamines and serotonin

Answer 5

Monoamines Oxidase

Question 6

Byproducts of biochemical pathways , such as those involved in neurotransmitter or drug inactivation

Answer 6

Metabolites

Question 7

Process that involves transport of a neurotransmitter from the extra cellular fluid back into the same cell that released it

Answer 7

Reuptake

Question 8

Neurotransmitter, related to NE and EPI that belongs to catecholamines

Answer 8

Dopamine (DA)

Question 9

NT related to DA that belongs to catecholamines. Also functions as a hormone secreted by chromaffun cels of the adrenal medulla

Answer 9

Norepinephrine

Question 10

NT found in the central and peripheral nervous system and synthesized by serotonergic neurons

Answer 10

Serotonin (5-HT)

Question 11

Amino acid characterized by the presence of an insole group. Precursor to 5-HT

Answer 11

Tryptophan

Question 12

The ionized form of glutamic acid. It is an excitatory amino acid neurotransmitter of the CNS

Answer 12

Glutamate

Question 13

Amino acid that is the principal inhibitory neurotransmitter in the CNS

Answer 13

GABA

Question 14

Enzyme that catalyzes the slow lest step in a biochemical pathway. It determines the overall rate of product formation

Answer 14

Rate - limiting enzyme

Question 15

When ___ binds to its receptors on the postsynaptic membrane, it typically causes an influx of positively charged ions (NA+) and (ca2+) into the postsynaptic neuron resulting in depolarization… more likely for action potential

Answer 15

Glutamate

Question 16

When ____ binds to its receptors on the postsynaptic membrane, it typically causes an influx of negatively charged chloride ions into the post sypnatic neuton. Leads to hyperpolerization of the membrane potential less likely to fire action pot

Answer 16

gAba

Question 17

Choline leads to _____

Answer 17

Acetylcholine

Question 18

L-tryptophan leads to ….

Answer 18

5-HT

Question 19

Glutamine leads to___ which leads to ___

Answer 19

Glutamate, y-aminobutryicacid (gaba)

Question 20

Dopinergic system is found mostly in ___

Answer 20

Midbrain

Question 21

Dopaminertic system are labeled ___

Answer 21

A

Question 22

What is nirgrostriaral pathway important for

Answer 22

Motor function (basal ganglia)

Question 23

What is Mesolimbic pathway important for ?

Answer 23

Reward

Question 24

Mesolimbic pathway

______——-> limbic system (including ____)

Answer 24

ventral tegmental area, n. Accumbens

Question 25

What is noradrenergic system important for

Answer 25

Altertness

Question 26

How is serotrngic system labeled ?

Answer 26

B

Question 27

Which system is Raphae nuclei (dorsal and median ) or (b7, b8) associated with ?

Answer 27

Serotrnergic sysfen