ciclo de krebs Flashcards

1
Q

donde ocurre?

A

mateix mitocondrial

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2
Q

como pasa de piruvato a acetyilcoa?

A

deshidrogenasa de piruvato

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3
Q

que reduce la act de la enzima isocitrato?

A

altos niveles de ATP y NADH

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4
Q

que estimula la act de la enzima isocitrato?

A

altos niveles de ADP (diciendo q se necesita energia)

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5
Q

rate limiting step del ciclo de krebs

A

enzima isocitrato

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6
Q

las hormonas interfieren en el ciclo de krebs?

A

no

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7
Q

que enzima tmb participa en la cadena transportadora de electrones?

A

succinil deshidrogenasa

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8
Q

que añade la enzima succinato tiocina?

A

grupo fosfato y GDP para formar GTP

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9
Q

que pasa si se dañan los tejidos donde sucede el ciclo de krebs?

A

hiperamonemia, enfermedad hepatica avanzada. perdida de conocimiento, convulciones (formacion reducida de ATP)

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10
Q

relacion de amoniaco con ciclo de krebs

A

disminuye intermediarios, inhibe la descanlxilacion oxidativa del a- cetoglutarato

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11
Q

por que el ciclo de krebs es la via comun final para la oxidacion de los carbs, lipidos y proteinas?

A

pq la glucosa, los acidos grasos y casi todos los amoniacos se metabolizan hacia acetil co a del ciclo

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12
Q

producto final de ciclo de krebs

A

3 NADH
1 FAD
1GTP

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