Viral replication strategies

Question 1

What are the steps for dsDNA virus to replicate its nuclear material?

Answer 1

dsDNA transcribed by host or viral DNA polymerase

create new dsDNA

Question 2

What are the steps for dsDNA virus to create proteins?

Answer 2

dsDNA transcribed by host DNA-dependent RNA polymerase to produce virus specific mRNA

virus mRNA translated to proteins in ribosomes

Question 3

What are the steps for +ssRNA virus to replicate its nuclear material?

Answer 3

+ssRNA transcribed by RNA-dependent RNA polymerase

create new +ssRNA

Question 4

What are the steps for +ssRNA virus to create proteins?

Answer 4

+ssRNA can be used by ribosomes to be translated into viral proteins

Question 5

What are the steps for -ssRNA virus to replicate its nuclear material?

Answer 5

-ssRNA transcribed by RNA-dependent RNA polymerase

create new -ssRNA

Question 6

What are the steps for -ssRNA virus to create proteins?

Answer 6

-ssRNA is transcribed to +ssRNA by RNA-depdendent RNA polymerase

+ssRNA can be used by ribosomes to be translated into viral proteins

Question 7

What are the steps for RNA retrovirus to replicate its nuclear material?

Answer 7

Viral reverse transcriptase converts RNA into DNA, which is inserted into host cell genome

DNA-dependent RNA polymerase transcribes mRNA as normal from host genome - inadvertently transcribing viral +ssRNA (mRNA) - which is it’s nuclear material

Question 8

What are the steps for RNA retrovirus to produce proteins?

Answer 8

Viral reverse transcriptase converts RNA into DNA, which is inserted into host cell genome

DNA-dependent RNA polymerase transcribes mRNA as normal from host genome - inadvertently transcribing viral mRNA proteins