How Do Nerves Work 1 Flashcards

1
Q

what is selective permeability?

A

allows the cell to control which molecules pass through the cell membrane either into or out of the cell through passive transport, active transport and transport using vesicles

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2
Q

describe the structure of the plasma membrane?

A

dynamic structure in which proteins float in a sea of lipids

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3
Q

what are the 3 major groups of lipids in a membrane?

A

phospholipid
glycolipid
cholesterol

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4
Q

what is the structure of a phospholipid?

A

hydrophilic polar head -> phosphate group - usually attached to an alcohol e.g. choline
glycerol
non-polar hydrophobic tails -> fatty acid chains
ester bonds

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5
Q

what are fatty acids?

A

Long hydrocarbon chain of various lengths and degrees of unsaturation terminated by a carboxylic acid group.

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6
Q

why do we need differing chain length and saturation of fatty acids?

A

control fluidity of membrane, shorter chain length and saturated -> more fluid

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7
Q

what is the structure of a glycolipid?

A

galactose
sphingosine
1 fatty acid chain

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8
Q

what is the purpose of cholesterol in the membrane?

A

gives membrane rigidity
Cholesterol groups are orientated in a specific way within the membrane which enables them to reduce fluidity of the membrane

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9
Q

in the lipid bilayer the hydrophobic tails are held together by what?

A

van der waals forces

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10
Q

in the lipid bilayer the hydrophilic head are held together by what?

A

ionic bonding

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11
Q

how is fluidity of the membrane controlled?

A

by lipids
saturation and chain length of fatty acids
amount of cholesterol

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12
Q

what carry out most of membrane processes?

A

proteins

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13
Q

what kind of transport allows nerve impulses?

A

active transport -> sodium potassium pump

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14
Q

when a neurone is at rest (no AP) where is K+ and Na+?

A

lots of K+ inside the cell
Na+ outside.

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15
Q

what are the 4 steps in the transmission of an action potential?

A

action potential -> depolarisation
repolarisation
refractory period
hyperpolarisation

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16
Q

what happens during depolarisation?

A

Na+ moves inside the cell

17
Q

what happens during repolarisation?

A

K+ move outside, Na+ stay inside

18
Q

what happens during the refractory period?

A

back to normal -> K+ returns inside, Na+ returns outside

19
Q

what happens during hyperpolarisation?

A

more K+ outside than Na+ inside

20
Q

how does anaesthetic work?

A

Blocks voltage gated sodium channels