Calculation Of Doses: General Consideration Flashcards

1
Q

Dose

A

It is the quantitative amount administered or taken by a patient for the intended medicinal effect.

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2
Q

Single Dose

A

The amount taken at one time

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3
Q

Daily Dose/ Total Dose

A

The amount taken during the course of therapy

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4
Q

Dosage Regimen

A

The schedule of dosing
(Ex. QID for 10 days)

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5
Q

Usual Adult Dose

A

The amount that ordinaripy produces the medicinal effect intended in the adult patient

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6
Q

Usual Pediatric Dose

A

Is similarly defined for the infant or child patient

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7
Q

Usual Dosage Range

A

The quantitative amounts of the drug that may be prescribed within the guidelines of usual medical practice

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8
Q

Median Effective Dose

A

The amount that produces the desired intensity of effect in 50% of the individuals tested

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9
Q

Median Toxic Dose

A

The amoumt that produces toxic effects in 50% of the individuals tested

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10
Q

Loading Dose

A

Or Priming Dose, a larger-than-usual initial dose may be required to achieve the desired blood drug level

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11
Q

Median Effective Concentration

A

The minimum concentration to produce the drug’s desired effects in a patient

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12
Q

Minimum Toxic Concentration (MTC)

A

The concentration that produces dose-related toxic effects

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13
Q

Monotherapy

A

Primary Drug Treatment

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14
Q

Adjunctive Therapy

A

Additional to or supportive of a different primary treatment

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15
Q

Prophylactic Doses

A

Administered to protect the patient from contradicting a specific disease
(Ex. Vaccines)

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16
Q

Dosage Forms

A

Contains pharmaceutical ingredients , which provides physical features, stability requirments, and aesthetic characteristics desired for optimal therapeutic effects

17
Q

Pharmaceutical Ingredients

A

Solvents
Vehicles
Preservatives
Stabilizers
Solubilizers
Binders
Fillers
Disintegrants
Flavorants
Colorants

18
Q

1 teaspoonful (tsp)

A

5ml

19
Q

1 tablespoonful (tbsp)

A

15ml

20
Q

20 drops (gtt)

A

1ml

21
Q

Number of doses

A

Number of doses= Total quantity
——————
Size of dose

22
Q

Size of Dose

A

Size of Dose= Total Quantity
——————–
Number of doses

23
Q

Total Quantity

A

Total Quantity= # of Doses× Size of Doses

24
Q

Low-Dose Therapy

A

The administration of doses that are much smaller than the usual dose of a drug
Ex.
Use of aspirin in 81 mg amounts ( rather than the usual dose of 325mg) to lower the risk of heart attack and clot-related stroke
Low-dose oral contraceptive use
Low-dose postmenopausal hormone therapy

25
Q

High Dose Theraphy

A

The administration of doses that are much larger than the usual dose of a drug
Ex.
Commonly associated with the chemotherapeutic treatment of cancer. Through increased dose intensity, to kill tumor cells.
High-dose use of progestin in the treatment of endometriosis
High-dose influenza vaccinatiom of the elderly.

26
Q

Fixed-Dose Combination Products

A

Products containing two or more therapeutic agents in fixed-dose combinations.

27
Q

Tablet Splitting and Crushing

A

A number of tablets are scored, or grooved, to allow breaking into approximately equal pieces ( usually halves)
This allows dosage flexibility, particularly when a patient is started at a half dose and then is titrated up to a full dosage level
It also enables a patient to take product at a strength that is not otherwise available