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Rotación 1 > Ibuprofeno > Flashcards

Ibuprofeno Flashcards

1
Q

Mecanismo de acción 1

A

Bloqueadores de la ciclooxigenasa.
Impide la sintesis de protaglandinas.
Competitivos reversibles, bloquean el canal hidrofobo de la COX.

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2
Q

Mecanismo de accion 2

A

Via lipoxigenasa
Impide produccion de radicales libres, liberacion de enzimas lisosomales, interleuquinas

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3
Q

Mecanismo de accion 3

A

Proteinas G modificando la activacion de las celulas que intervienen en los estadios iniciales de la inflamacion y produccion citoquinas

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4
Q

COX 1Y 2

A

Derivado del acido propionico

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5
Q

Efecto

A

Analgesico, antitermico, antiinflamatorio, antiagregante plaquetario, uricosurica

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6
Q

RAM

A

Pirosis, dispepsia, diatesis hemorragica, anemia hemolitica, agranulocitosis, anemia aplasica, trompocitopenia, hepatoxicidad, sindrome de steven johnson

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Rotación 1 (31 decks)

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