Polycystic Kidney Disease Flashcards

1
Q

What is PKD?

A

A genetic condition where kidney tissue is replaced with fluid-filled cysts

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1
Q

What are the 2 genes affected in ADPKD?

A
  • PKD1 chromosome 16 - most common
  • PKD2 chromosome 4
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2
Q

What are complications of ADPKD?

A
  • Chronic pain
  • HTN
  • Gross haematuria
  • Recurrent UTI
  • Renal stones
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3
Q

How is ADPKD managed?

A
  • Tolvaptan can slow the development of cysts
  • Anti-HTN
  • Analgesia
  • Abx
  • Dialysis/Transplant for end stage renal failure
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