Rifamycins

Question 1

Name the Rifamycin’s

Answer 1

Rifabutin (tuberculosis)
Rifampicin (tuberculosis)
Rifaximin (E. coli)

Question 2

Rifamycin’s MOA

Answer 2

Inhibits bacterial RNA polymerase

Question 3

Are Rifamycin’s bactericidal or bacteriostatic?

Answer 3

Bactericidal

Question 4

Rifamycin’s Adverse Effects (common)

Answer 4

GI upset
Rash

Question 5

Rifamycin’s Counselling

Answer 5

Rifampicin and rifabutin can make the pill less effective

Your urine, faeces, sweat and tears may become orange-red and soft contact lenses may be permanently stained.

Interacts with many drugs