antihyperlipidermics + diuretics Flashcards

1
Q

diuretics in proximal convoluted tubule

A

carbonic anhydrase inhibitors, osmotic diuretics

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2
Q

diuretics in loop of henle

A

loop diuretics

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3
Q

diuretics in distal convoluted tubule

A

thiazides

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4
Q

diuretics in collecting ducts

A

aldosterone antagonists, ADH antagonists

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5
Q

thiazide diuretics w/ different name

A

chlorthalidone, metolazone

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6
Q

K+ sparring diuretic names

A

spironolactone, eplerenone

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7
Q

statin MOA

A

HMG CoA reductase inhibitor

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8
Q

choles MOA

A

bile acid sequestering agent

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9
Q

fibr MOA

A

inhibits lypolysis

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10
Q

ocumab MOA

A

PCSK-9 inhibitor

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11
Q

ezetimibe MOA

A

cholesterol absorption in SI

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12
Q

thiazide MOA

A

inhibit reabsorption in distal convoluted tubule

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13
Q

semide MOA

A

inhibits reabsorption in loop of henle (loop diuretic)

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14
Q

k+ sparring diuretics MOA

A

competes w/ aldosterone for receptors in distal renal tubules

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15
Q

which antihyperlipidemics decrease LDL only

A

ocumab, bempedoic acid (nexletol), choles, inclisarin

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16
Q

O3 fatty acid names

A

lovaza, vascepa

17
Q

statin indications

A

hypercholesterolemia/triglyceridemia, CVD, CHD, ASCVD, AMI, angina, stroke, diabetes

18
Q

choles indications

A

dyslipidemia

19
Q

fibr indications

A

hypertriglyceridemia, hypocholesterolemia

20
Q

thiazide indications

A

hypertension edema, fluid retention

21
Q

semide indications

A

fluid management

22
Q

k+ sparring diuretic indications

A

systolic CHF

23
Q

choles DDIs

A

warfarin, statins/fibrates, amiodarone

24
Q

gemfibrozil DDIs

A

statins, ezetimibe, CYP2C8, warfarin

25
Q

statin ADEs

A

pregnancy category X, nasopharyngitis, insomnia, malaise, increased hepatic function

26
Q

choles ADEs

A

osteoporosis

27
Q

fibr ADEs

A

increased serum transaminases

28
Q

ocumab ADEs

A

flu-like symptoms

29
Q

ezetimibe ADEs

A

fatigue, increased serum transaminases

30
Q

thiazide ADEs

A

photosensitivity, orthostatic hypotension

31
Q

semide ADEs

A

hyponatremia, hyperuricemia, leg cramps

32
Q

K+ sparring diuretics ADEs

A

gynecomastia