NSAIDs Flashcards
1
Q
Celecoxib (g)
A
Celebrex (b)
2
Q
Diclofenac (g)
A
Voltaren, Voltaren Gel (b)
3
Q
Ibuprofen (g)
A
Advil, Motrin (b)
4
Q
Indomethacin (g)
A
Indocin, Tivorbex (b)
5
Q
Meloxicam (g)
A
Mobic (b)
6
Q
Naproxen (g)
A
Aleve, Naprosyn (b)
7
Q
MOA
A
block COX-1 and COX-2 enzymes to inhibit formation of prostaglandins to decrease inflammation, aleviate pain and reduce fever
8
Q
common adverse effects
A
increased BP
photosensitivity
9
Q
rare adverse effects
A
GI bleeding/ulceration
10
Q
counseling pts
A
take with food
don’t take if cardiac issues, kidney dysfunction, or pregnant
use sunscreen or sun-protective clothing
11
Q
clinical pearls
A
celecoxib, diclofenac, and meloxicam have increased selectivity for COX-2, making their risk for GI complications lower and risk for MI/stroke higher
