CNS - Meningitis, encephalitis, brain abscess Flashcards

1
Q

Meningitis

Classification

A
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2
Q

Meningitis vs encephalitis

Distinguishing feature

A
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3
Q

Bacterial meningitis

Common causative pathogens

A
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4
Q

Bacterial meningitis

Most likely causative organism across age groups and demographics

A
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5
Q

Viral meningitis

Most common pathogens

A
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6
Q

Subacute and malignant meningitis

Causes

A
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7
Q

Bacterial meningitis

Pathophysiology

A
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8
Q

Viral meningitis

Pathophysiology

A
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9
Q

Meningitis

S/S

A
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10
Q

Meningitis

History taking questions

A
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11
Q

Meningitis

P/E

A
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12
Q

Meningitis

Biochemical Ix

A

Microbiological Ix:
- Blood culture
- CSF analysis by lumbar puncture; CSF smear, culture with sensitivity testing, antigen detection and PCR
- Blood and urine for viral culture and PCR
- Throat, rectal swabs for viral culture and PCR
- Serology

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13
Q

Meningitis

Compare CSF parameters between bacterial vs viral vs fungal infection

A
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14
Q

Meningitis

Microbiological workup

A

Blood culture
* Cultures should be obtained before administration of antimicrobials
* Useful when lumbar puncture is delayed or deferred due to increased ICP

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15
Q

Meningitis

Radiological Ix

A
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16
Q

Meningitis

Management of increased ICP

A
17
Q

Meningitis

Antimicrobials

A
18
Q

Meningitis

Dexamethasone use
- Indication
- MoA
- Rationale

A
19
Q

Meningitis

Medical treatment in children

A
20
Q

Meningitis

Complications

A
21
Q

Meningitis

Prevention

A
22
Q

Anti-TB medications
- MoA
- Side effects

A
23
Q

Anti-TB medication use with dexamethasone

Indications

A
24
Q

Lumbar puncture

Contraindications
Complications

A
25
Q

Ddx neutrophilic and lymphocytic meningitis

A
26
Q

Encephalitis

Definition
Difference with meningitis

A
27
Q

Encephalitis

Acute and chronic causes

A
28
Q

Post-infectious viral encephalitis

Causes

A
29
Q

Difference between primary and post infectious viral encephalitis

A
30
Q

Encephalitis

Clinical presentation

A
31
Q

Encephalitis

D/dx

A
32
Q

Encephalitis

Investigations

A
33
Q

Encephalitis

Treatment (excluding general and ICH treatment)

A
34
Q

Brain abscess

Routes of spread

A
35
Q

Brain abscess

Causative pathogens

A
36
Q

Brain abscess

Clinical presentation
Disease progression

A
37
Q

Brain abscess

Investigation

A
38
Q

Brain abscess

Treatment
Complications

A