Cell Membranes and Transport Flashcards

1
Q

What is the fluid mosaic model?

A

Fluid - Phospholipid molecules within the layer can move relative to each other
Mosaic - The proteins within the bilayer are of different sizes and shapes and form different patterns

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2
Q

What are intrinsic proteins?

A

Proteins found within the bilayer, includes channel and carrier proteins

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3
Q

What are extrinsic proteins?

A

Proteins found at the edges of the phospholipid bilayer

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4
Q

Name factors that affect permeability

A
  • Temperature
  • Organic Solvents
  • pH
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5
Q

How does temperature affect permeability of the plasma membrane?

A

As temperature increases, the phospholipids have more kinetic energy and move more, increasing fluidity and permeability of the membrane

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6
Q

What happens to the membrane if the temperature becomes too high?

A

Channel and carrier proteins will become denatured
Cell will eventually break down completely

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7
Q

How do organic solvents affect permeability of the plasma membrane?

A

Organic solvents dissolve membranes, disrupting the cell. Increasing the permeability

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8
Q

Define diffusion

A

The passive movement of small non-polar molecules from an area of high concentration to an area of low concentration

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9
Q

State the factors that affect the rate of diffusion

A

-temperature
- Steepness of concentration gradient
- Size of molecule
- Diffusion distance

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10
Q

Define osmosis

A

Movement of water molecules from a region of high water potential to a region of lower water potential through a selectively permeable membrane

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11
Q

What is water potential ?

A

Negative value , fresh water = 0
A measure of the tendency of water molecules to move from one area to another

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12
Q

What is incipient plasmolysis?

A

Where the water potential = the solvent potential
- effect produced when plant cells are placed in isotonic solution
- Causes cell membrane to pull away from the cell wall in some areas
- Cell is neither plasmolysed nor turigd

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13
Q

What is facilitated diffusion?

A

Net movement of substances through a transport protein without the use of energy

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14
Q

Define active transport

A

The movement of substances from a low concentration to a high concentration, use of energy in the form of ATP

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15
Q

How does cyanide affect active transport?

A

Cyanide inhibits respiration and the formation of ATP, preventing active transport

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16
Q

What are two mechanisms of bulk transport?

A

Endocytosis
Exocytosis

17
Q

Phospholipid Heads

A

-Hydrophilic
Allow the movement of lipid soluble molecules , but not water molecules as they are polar

18
Q

Fatty acid tails

A

-Hydrophobic
- Point towards each other in the centre of the bilayer

19
Q

Channel Protein

A
  • Pores lined with polar molecules (hydrophillic)
  • Allowing charged ions through
    -Each protein is specific to one type of ion, open and close depending on the needs of the cell.
20
Q

Carrier Protein

A
  • Allows larger molecules through e.g. amino acid, water
    -Molecules attach to protein at its binding site and causes protein to change shape or rotate within membrane. Releasing the molecule the other side
21
Q

Explain co-transport and give an example

A

Type of facilitated diffusion that brings molecules and ions into the cell together on the same protein transport e.g. sodium-glucose co transport

22
Q

Cholesterol

A

Presents between phospholipids in animal cells, maintains the fluidity of the cell. Too much and the cell becomes turgid, too little and the cell will break apart

23
Q

What happens to animal and plant cells in hypotonic solution

A

Higher water solution to the cell
Animal - Cell swells and may lyse
(burst)
Plant - The cytoplasm and the vacuole swell and push against the cell wall; cell becomes turgid.

24
Q

What happens to animal and plant cells in hypertonic solution?

A
  • Water potential is higher in cell, solution has a lower water potential
    Animal - The cell shrinks
    Plant - The cytoplasm and vacuole shrink causing the cell membrane to pull away from the cell wall. This process is called plasmolysis and cell are said to be plasmolysed.
25
Q

What happens to animal and plant cells in isotonic solution?

A

Animal - animal cells optimal bathing medium, water potential of cell is equal to the water potential of the external medium at this point.
Plant - Cells become flaccid, this is the point of incipient plasmolysis

26
Q

What are the 2 types of endocytosis?

A

Pinocytosis and phegocytosis

27
Q

What is endocytosis?

A

The bulk intake of material by a cell by the formation of vesicle

28
Q

Pressure Potential

A

Always a positive value
Pressure exerted by the cell contents on the cell wall as water enters the vacuole

29
Q

What do channel and carrier proteins do to the rate of diffusion?

A

Increase it
- Initial increase due to concentration gradient becoming steeper, carrier & channel proteins facilitate the process.
- Rate of diffusion then levels off at a higher concentration gradient due to proteins being occupied

30
Q

Describe how bulk transport occurs in large particles entering the cell

A

Via endocytosis
1) the plasma membrane folds inwards
2) Plasma membrane continues to fold engulfing the material
3) Plasma membrane fuses to enclose the material

31
Q

Functions of the cell membrane

A
  • Separate the living cell from its non-living surroundings
  • control which substances pass into and out of the cell
  • cell recognition