development Flashcards

1
Q

germ lines

A

cells have different proteins and eventually develop into own type of cell (skin, muscle, bone, etc.)

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2
Q

processes that occur in animal development

A

controlled cell division, cell specialization, cell heredity, morphogenesis

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3
Q

what is cell specialization?

A

expression of different genes

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4
Q

what is cell heredity?

A

once cell starts to express specific genes, all cells formed from that cell will only ever develop into specific cell types

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5
Q

morphogenesis

A

spatial arrangement of specialized cells

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6
Q

control over cell division

A

most eukaryote cells do not have the ability to divide.

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7
Q

growth factorsand how it may be produced

A

these proteins must be present to complete cell cycle.

growth factors may be produced externally or internally to allow cells to pass checkpoints

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8
Q

in eukaryotes what stage are most specialized cells in.

A

in the 1st part of interphase G1

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9
Q

production of growth factors depends on…

A

conditions in and around the cell

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10
Q

membrane proteins main functions in development

A

carry signals, cell recognition.
membrane proteins involved in cell recognition and signalling can intereact with growth factors

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11
Q

cancer results when…

A

cells dividing too much. proteins producing a signal for cell division without a growth factor (no checkpoints)

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12
Q

example of skin cells with growth factors

A

divides until surrounded by other cells, if cells are removed, growth factors are produced and cell division occurs

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13
Q

when does cell specialization occur

A

through the turning off and on (expression) of genes

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14
Q

order of cell specialization

A

undifferentiated cell———> germ layer——> tissue cells with similar function—–> speicalized cell

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15
Q

3 processes that lead to specialization: chromatin (DNA and histones) packaging

A

adding methyl (CH3) to histobes causes chromatin to condense preventing transcription

adding acetyl (COH3) causes chromatin to unravel

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16
Q

3 processes that lead to specialization: single gene activation and when this happens

A

inactivation of X/Y chromosomes
whole chromosome condensed preventing transcription

maternal or paternal chromosomes are deactivated at random

happens when zygote has started to divide. all daughter cells have some chromosome deactivated

results in regions of organism with different alleles expressed (dog with 2 colours)

17
Q

methylation and cytosine prevents…

and during DNA replication…

A

methylation and cytosine prevents transcription

methylation states are copied to new DNA strands

18
Q

2 forms of heredity within organisms

A
  1. genetic code
  2. cell state (contents of cytoplasm and inactivated genes- epigenetic)
19
Q

what does inactivation genes result in?

A

cell heredity and increasing levels of specialization

once a cell enters a level of specialization, it cant change into anything else

20
Q

for gamete production is the inactivation of genes removed?

A

yes

21
Q

cell specialization in plants

A

only regions have cells that divide

these cells can develop into any type of specialized cell because genes have not been inactivated.

(only happens during animal development)

22
Q

gene expression
in prokaryotes

A

genes involved in related functions are grouped by operons

regulatory proteins can bind other molecules. this binding affects their ability to attach to the operator region of a gene

23
Q

operator

A

binds with regulatory protein, preventing transcription

24
Q

genes involved in building organic molecules are associated with…

A

repressible operons.
-gene expression is blocked when the product of the metabolic pathway is present

25
Q

genes involved in breaking down organic molecules are associated with

A

inducible operons
ex: lactose operon presence allows for transcription to occur

26
Q

2 types of feedback control in metabolic activity

A

feedback inhibition (quick)
gene expression (slow)

27
Q
  1. gene expression in eukaryotes
A

contents of cytoplasm of fertilized egg not equally distributed

after cell division, daughter cells have different proteins and RNA’s resulting them to express different genes

most genes are in an active state

28
Q

many__________ may be required for transcription to take place.

these_______ intereact with ________ near the gene

A

regulatory proteins

proteins, DNA

29
Q

some of the non coding DNA is involved in the…

A

regulation of gene expression

30
Q

oncogene

A

gene that causes cancer

31
Q

4 processes resulting in oncogene

A

gene moved (translocated) to a region of the chromosome that is more expressed

gene duplicated producing more cell growth factor

mutations to promotor region, resulting in increased transcription

mutation to gene that make it more effective in promoting cell division

32
Q

controlling gene expression at the mRNA level

A

most DNA on chromosomes dont code for amino acids.

some of the non-coding DNA is used to make microRNA’s

some microRNA’s bind with mRNA, degrading it or block its trabslation.