Ga-67 gallium citrate

Question 1

what other elements in same periodic group

Answer 1

iron and indium so similar physical and chemcal properties

Question 2

gallium 67 is a

Answer 2

trivalent cation

Question 3

how was ga discovered

Answer 3

testing for isotopes and it showed tumor imaging in animal models

Question 4

how is it produced

Answer 4

cyclotron produced by bombarding Zn-68

Question 5

half life and 4 energies

Answer 5

78 hrs, 93/185/300/394

Question 6

gallium is insoluble so what do we do about that

Answer 6

it is insoluble and has pH of 7.4 bc of hydroxide complexes (GaOH3) that form. so we add citrate (-3) ion which produces a soluble complex and dissolved in solution buffered to 4.5-8.0 pH

Question 7

behaves like….

Answer 7

iron in the body

Question 8

how is gallium transported

Answer 8

via lactoferrin and transferrin

Question 9

where is it stored

Answer 9

bone marrow and liver

Question 10

in first 24 hours…

Answer 10

10-30% excreted via urine and dependent on binding to plasam proteins

Question 11

increased serum iron leavels means

Answer 11

incresed excretion

Question 12

2nd 24 hours …

Answer 12

10% excreted via lg bowels which means high rad dose to lg bowel due to slow transit

Question 13

1 week…

Answer 13

65% of dose remains in pt

Question 14

kit comes in glass vials with_____ as a preservative

Answer 14

0.1% benzyl alcohol

Question 15

comes as what type of vial

Answer 15

multidose vial

Question 16

exp

Answer 16

7 days post cal