[4.1] structure of the cell-surface membrane Flashcards

1
Q

key feature of the phospholipid bilayer (8)

A
  • hydrophilic head
  • hydrophobic tails
  • cholesterol
  • glycolipids
  • glycoproteins
  • channel proteins (transmembrane protein)
  • carrier proteins
  • extrinsic proteins
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2
Q

what are the functions of the phospholipid bilayer?

A
  • acts as a barrier for many substances
  • maintains the shape of the cell and its internal environment
  • plays a vital role in cell recognition and communication
  • forms the boundary between the cell cytoplasm and the environment
  • allows different conditions to be established inside and outside of a cell
  • controls the movement of substances in and out of the cell
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3
Q

describe the structure of a phospholipid

A

glycerol attached to 2 fatty acid chains and an inorganic phosphate group (google it xoxo)

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4
Q

describe the heads and tails’ relationship with water

A
  • hydrophilic heads point to the outside of the cell-surface membrane as they are attracted to water
  • hydrophobic tails point to the centre of the cell-surface membrane as they are repelled by water
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5
Q

what are examples of aqueous environments hydrophobic fatty acid tails will be repelled by? (7)

A
  • water
  • blood plasma
  • cell sap
  • tissue fluid
  • cytoplasm
  • matrix (mitochondria)
  • stroma (chloroplast)
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6
Q

what is the function of channel proteins?

A

water-filled tubes to allow water-soluble ions to diffuse across the membrane

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7
Q

what is the function of carrier proteins?

A

bind to ions or molecules eg. glucose & AAs, then changes shape so they can move across the membrane

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8
Q

what is the function of extrinsic proteins?

A
  • give mechanical support to the membrane
  • in conjunction with glycolipids, they act as cell receptors for molecules such as hormones
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9
Q

what are general functions of the proteins in the membrane?

A
  • provide structural support
  • act as channel transporting water-soluble substances across the membrane
  • allow active transport across the membrane through carrier proteins
  • form cell-surface receptors for identifying cells
  • helps cells adhere together
  • act as receptors eg. hormones
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10
Q

what are the functions of cholesterol in the membrane?

A
  • add strength
  • prevent leakage of water and dissolved ions
  • reduce lateral movement of other molecules including phospholipids by pulling together the tails, limiting their movement and that of other molecules
  • make the membrane less fluid at high temperatures
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11
Q

what is a glycolipid made up of?

A

a carbohydrate covalently bonded with a lipid

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12
Q

what are the functions of glycolipids in the membrane?

A
  • act as recognition sites
  • help maintain the stability of the membrane
  • helps cells to attach to one another and so form tissues
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13
Q

what are glycoproteins made of?

A

carbohydrate chains attached to many extrinsic proteins

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14
Q

what are the functions of glycoproteins?

A
  • act as recognition sites
  • helps cells to attach to one another and so form tissues
  • allows cells to recognise one another eg. lymphocytes can recognise an organism’s own cells
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15
Q

what are the functions of membranes within cell?

A
  • control entry and exit of materials in organelles eg. mitochondria, chloroplast
  • separate organelles from cytoplasm so that specific metabolic reactions can take place within them
  • provide an internal transport system eg. ER
  • isolate enzymes that might damage the cell eg. lysosomes
  • provide surfaces on which reactions can occur eg. protein synthesis using ribosomes on RER
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16
Q

why can most molecules not freely diffuse across the cell-surface membrane?

A
  • not soluble in lipids so cannot pass though PLB
  • too large to pass through the channels in the membrane
  • same charge as charge on protein channels so even if they are small enough to pass through, they are repelled
  • polar so have difficulty passing through non-polar hydrophobic tails in PLB
17
Q

why is the arrangement of various molecules on the cell-surface membrane known as the fluid-mosaic model?

A
  • fluid because individual phospholipid molecules can move relative to one another, gives the membrane a flexible structure that is constantly changing shape
  • mosaic because the proteins that are embedded in the PLB vary in shape, size and pattern