Haemostasis Flashcards

1
Q

What does heamostasis mean?

A

To stop bleeding from a cut or injury to prevent further injury

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2
Q

Describe haemostasis ?

A

Process of forming clots in the walls of damaged blood vessels and preventing blood loss

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3
Q

What is vasoconstriction

A

When muscles contract
Platelets meet damaged blood vessel clot needs to form

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4
Q

Platelet plug

A

Platelets stick to damaged endothelium to form platelet plug, temporarily sealing the break in vessel wall

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5
Q

What is thrombopoietin?

A

A hormone produced by the liver and kidney which regulates production of platelets

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6
Q

Haemostasis involves the following process?

A

Vasoconstriction
Formation of platelet plug
Blood coagulation

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7
Q

How does haemostasis begin?

A

Begins with chemicals being released from damasked tissue cells extrinsic pathway and form platelets intrinsic pathway

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8
Q

Extrinsic
Intrinsic

A

Extrinsic occurs immediately
Intrinsic is slower

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9
Q

Blood clotting factors

A

Thromboplastin
Prothrombin
Fibrinogen

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10
Q

What is the von williebrand factor?

A

Protein secreted by endothelial cells that connects platelets to collagen

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11
Q

Explain Von williebrand disease

A

Inherited bleeding disorder from low levels of von williebrand factor

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