Pharmacology equations Flashcards
1
Q
What is the Henderson hasselbalch equation?
For acids?
For bases?
A
Ph = pKa + log (proton acceptor / proton donor)
Ph = pKa + log (A-/AH)
Ph = pKa + log (B/BH+)
2
Q
What is the drug receptor dissociation equation?
Association constant relationship?
A
KD = [D] + [R] / [DR]
KA = 1/KD
3
Q
What is the simple and full equation for drug receptor fractional occupancy?
A
r = [DR] / RT
Full:
r = [D] / KD + [D]
4
Q
What are the basic and full equations for drug receptor observed response?
A
E = er
Full:
E = e [D] / KD + [D]
5
Q
What is the michaelis mention equation?
A
V = Vmax [S] / (Km + [S])
