Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

702 > Osteoarthritis > Flashcards

Osteoarthritis Flashcards

1
Q

What is the most common joint disease?

A

Osteoarthritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are risk factors for OA?

A
  • Obesity
  • Sex (female)
  • Occupation
  • Participation in certain sports
  • History of joint injury or surgery
  • Genetic predisposition
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are signs of OA?

A
  • Mono/oligoarticular asymmetrical involvement
  • Local tenderness
  • Limited motion with passive/active movement
  • Bone proliferation or synovitis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are symptoms of OA?

A
  • Pain
  • Deep, aching
  • Stiffness in affected joint
  • Usually <30 minutes duration
  • Often related to weather
  • Limited joint motion
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are some distinguishing features that can help you distinguish OA as opposed to RA?

A
  • Gradual onset >50 years
  • Localized joint symptoms
  • Larger, weight bearing joints
  • Brief <30 minute attacks
  • Pain with use
  • Unilateral
  • No auto-antibodies
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the most common joint locations for OA?

A

Hands, knees, hips

(Can also be spine and feet)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

How is OA diagnosed?

A

Through history, physical exam, X-ray findings, lab testing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are goals of OA therapy?

A
  • Distinguish between primary and secondary OA
  • Clarify joints involved
  • Assess response to prior therapies
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is primary OA?

A

Most common form with no identifiable cause

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is secondary OA?

A

Associated with a known cause such as inflammation, trauma, metabolic/endocrine disorders, or congenital factors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are non-pharm options for OA?

A
  • Exercise
  • Self-management programs
  • Weight loss
  • Tai Chi
  • Cane
  • Knee braces
  • CBT
  • Yoga
  • Thermal interventions (hot or cold)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the first step in OA treatment?

A

Patient education

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What non-pharm treatments should NOT be done in OA?

A
  • TENS (transcutaneous electrical stimulation)
  • Manual therapy
  • Massage therapy
  • Modified shoes
  • Pulsed vibration therapy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the first line treatment for ANY OA location?

A

Oral NSAIDs (lowest possible dose and duration)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are second and third line treatments for OA?

A
  • Topical NSAIDs
  • Intra-articular steroids
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What drug interaction should you avoid with NSAIDs?

A

ACEi/ARB/Loop diuretic

17
Q

What kind of NSAID is better for patients at higher risk of GI problems?

A

COX-2 selective (-coxib)

18
Q

What kind of OA is topical NSAIDs most used in (location)?

A

Knee OA

19
Q

What are counseling tips for topical NSAIDs

A
  • Wash hands afterwards (unless applying to hands)
  • Avoid contact with open wounds
  • Avoid touching eyes, nose, mouth after using
  • Less ADEs than oral
20
Q

What types of OA is IA steroids strongly recommended?

A

Knee and hip

21
Q

How long does it take for IA steroids to kick in and how long should they last?

A

2-3 days to work and last 4-8 weeks

Should be given no more than every 3 months (risk of systemic side effects)

22
Q

What are relative contraindications for IA steroids?

A
  • Active superficial infections
  • Suspected joint infection
  • Unstable coagulopathy
  • Uncontrolled diabetes
  • Broken skin at the injection site
23
Q

What are benefits of acetaminophen?

A

Less GI and CV effects than NSAIDs

24
Q

When can tramadol be used?

A
  • Failed treatment with APAP or topical NSAIDs
  • Contraindications to oral NSAIDs
  • Unable to receive IA steroids
  • Add-on to APAP and/or oral NSAIDs
25
Q

What is the only centrally acting agent for chronic pain that is approved for OA?

A

Duloxetine

26
Q

What is recommended against in hand OA but supported in knee OA?

A

Topical capsaicin

27
Q

What is recommended against in knee/hip OA but supported in hand OA?

A

Chondroitin

28
Q

What pharmacologic treatments are recommended against in OA?

A
  • Bisphosphonates
  • IA hyaluronic acid injections
  • Non-tramadol opioids
  • Colchicine
  • Fish oil
  • Vitamin D
  • Glucosamine (can be in combo with chondroitin)
  • Hydroxychloroquine
  • Methotrexate
  • TNF inhibitors
  • IL-1 antagonists

702 (15 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions