cell death Flashcards
1
Q
what is apoptosis
A
programmed cell death
2
Q
what is necrosis
A
death by injury
3
Q
why does apoptosis occur
A
proper development and to destroy cells that pose a threat to the organism (i.e infected cells/ DNA damaged cells, cancer cells
4
Q
what happens during apoptosis
A
chromosomal DNA is usually fragmented, chromatin condenses and nucleus breaks up into small pieces, cell shrinks+ breaks up, and then the fragments are phagocytosed
5
Q
how may apoptosis be triggered
A
ligation of cell surface receptors, DNA damage, treatments with cytotoxic drug or irradiation. lack of survival signals, contradictory cell cycle signals, developmental death signals
6
Q
A
