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Pharmacology 1 > Test3 Neuropharmacology > Flashcards

Test3 Neuropharmacology Flashcards

1
Q

the study of drugs that alter processes controlled by the nervous system

A

neuropharmacology

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2
Q

the process of an action potential (electrical impulse) being delivered toward the axon

A

synaptic transmission

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3
Q

drugs are almost always

A

reversible

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4
Q

from precursor molecules-potential target from drug therapy

A

transmitter synthesis

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5
Q

in vesicles

A

transmitter storage

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6
Q

stimulated by electrical impulse

A

transmitter release

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7
Q

the body’s own natural process is a reversible binding process

A

receptor binding

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8
Q
  1. recycled
  2. degraded by enzymes (killed)
  3. diffused and float away
A

termination of transmission

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9
Q

after is disassociates with its receptor

A

termination of transmission

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10
Q

ultimately the impact of a drug on a neuronally regulated process is dependent on the ability of that drug to directly or indirectly influence receptor activity on target cells

A

drug effects

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11
Q

electrical impulse

A

axonal conduction

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12
Q

drugs can increase or decrease or cause production of other neurotransmitters

A

transmitter synthesis

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13
Q

agonist/antagonist

A

receptor binding

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14
Q
  1. blockade of reuptake

2. inhibit transmitter degradation

A

termination of transmitter action

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15
Q

neurotransmitter for synaptic NS (sweat glands) and neurotransmitter for parasympathetic NS

A

acetylcholine

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16
Q

sympathetic neurotransmitter except for sweat glands

A

norepinephrine

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17
Q

adrenaline-in kidneys

A

epinephrine

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18
Q

CNS neurotransmitter, dilates the vasculature of the kidneys

A

dopamine

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19
Q

dramatically enhance selectively

A

receptors

20
Q

nerve-parasympathetic and sympathetic NS

A

nicotinic n

21
Q

muscles-somatic motor system

A

nicotinic m

22
Q

sweat glands-most organ

A

muscarinic

23
Q

eyes dilate, constriction of arteries and veins and prostate, contraction of sphincter, no urine

A

alpha 1

24
Q

whoa receptor-shuts down additional release of neurotransmitter in the synapse

A

alpha 2

25
Q

increase heart rate, increase contraction, increase SA and AV node

A

beta 1 agonist

26
Q

decrease heart rate, decrease contraction, increase SA and AV node

A

beta 1 antagonist

27
Q

dilation of arteries and bronchi in lungs, relaxation of uterus, glycogenolysis, and increase muscle contraction

A

beta 2

28
Q

dilation of kidney vasculature

A

dopamine

29
Q

destroyed by acetylcholinesterase

A

acetylcholine

30
Q

recycled and restored/metabolized by MAIOs monoamine oxidase

A

norepinephrine

31
Q

metabolized by the liver later

A

epinephrine

32
Q

muscarinic agonist

A

bethanechol

33
Q

muscarinic agonist used for glaucoma

A

pilocarpine

34
Q

reversibly bind to muscarinic receptors

A

muscarinic agonist

35
Q

muscarinic agonist have what type of effects?

A

cholinergic effects

36
Q

muscarinic agonist have what type of effects?

A

anticholinergic effects

37
Q

what is an example of an muscarinic antagonist?

A

atropine

38
Q

a competitive blockade at the muscarinic receptors

A

muscarinic antagonist

39
Q

prevent degradation of acetylcholine synapse

A

cholinesterase inhibitors

40
Q

what is an example of an cholinesterase inhibitor?

A

physostigmine

41
Q

nicotinic m antagonist

A

neuromuscular blocking agents

42
Q

long acting neuromuscular blocking agent

A

tubocurarine

43
Q

intermediate acting neuromuscular blocking agent

A

atracurium

44
Q

short acting neuromuscular blocking agent

A

mivacurium

45
Q

ultra short acting neuromuscular blocking agent

A

succinylcholine

46
Q

blocks nicotinic n receptors at the ganglionic level

A

ganglionic clockers

47
Q

what is an example of a ganglionic blocker?

A

mecamylamine

Pharmacology 1 (3 decks)

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