URINARY Section 4: Contrast induced nephropathy

Question 1

Allergic reactions in contrast induced nephropathy

Answer 1

Allergic reactions are NOT considered a risk factor for CIN.

Question 2

“Risk Factors” for CIN

Answer 2

pre-existing renal insufficiency
diabetes mellitus (even more so with pre-existing renal insufficiency)
cardiovascular disease with CHF
dehydration
myeloma.

Question 3

What supposedly decreases the incidence of CIN?

Answer 3

Hydration via IV with 0.9% normal saline 6-12 hours before and continuing 4-12 hours after contrast administration in patients with chronic renal insufficiency

(Mechanism is diluting Cr levels)

Oral dehydration - shown not to work