electrophysiological methods Flashcards
1
Q
what is single cell recording
A
- Uncommon method for studying humans
- Relevant for research with animals
Patch clamp technique - enters nerve cells and records action potentials
- Relevant for research with animals
2
Q
what does an EEG do
A
- Measures electrical activity from the scalp
- Conductivity of skull between 1/40 and 1/80 of the conductivity of the brain
We are only picking up a tiny fraction of actual brain activity
- Conductivity of skull between 1/40 and 1/80 of the conductivity of the brain
3
Q
what is required for an EEG of cognition
A
active and relaxed activity
4
Q
describe electromyography (EMG)
A
- Measures muscle response
Detects invisible neuromuscular activity - used to detect emotions in psychological experiments
5
Q
what is electrodermal activity
A
EDA refers to the variation of the electrical conductance of the skin in response to sweat secretion.
6
Q
describe event related potentials (ERPs)
A
Stimulus onset = event to which we relate the potentials we are measuring
- Polarity - positive or negative
- Latency - how long after onset
- Amplitude
- Topographic distribution
7
Q
what is an open brain EEG
A
- recording electro-encephalographic signals directly from the surgically exposed cerebral cortex.
- It detects intraoperatively the cortical regions with substantial epileptiform interictal discharges. Often used simultaneously with cognitive testing.
- Promising technique as implants for use of brain-computer interfaces (direct neural interfaces that provide control of prosthetic, electronic, or communication devices via direct use of the individual’s brain signals).
8
Q
describe Magneto-encephalo-graphy (MEG)
A
- a functional neuroimaging technique for mapping brain activity by recording magnetic fields
MEG outperforms EEG with respect to spatial resolution
9
Q
strengths of ERPs and ERFs
A
- high temporal resolution
Direct measure of neural activity
10
Q
weaknesses of ERPs and ERFs
A
- Measures only a part of neural activity
- Poor spatial resolution