electrophysiological methods Flashcards

1
Q

what is single cell recording

A
  • Uncommon method for studying humans
    • Relevant for research with animals
      Patch clamp technique - enters nerve cells and records action potentials
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2
Q

what does an EEG do

A
  • Measures electrical activity from the scalp
    • Conductivity of skull between 1/40 and 1/80 of the conductivity of the brain
      We are only picking up a tiny fraction of actual brain activity
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3
Q

what is required for an EEG of cognition

A

active and relaxed activity

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4
Q

describe electromyography (EMG)

A
  • Measures muscle response
    Detects invisible neuromuscular activity - used to detect emotions in psychological experiments
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5
Q

what is electrodermal activity

A

EDA refers to the variation of the electrical conductance of the skin in response to sweat secretion.

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6
Q

describe event related potentials (ERPs)

A

Stimulus onset = event to which we relate the potentials we are measuring
- Polarity - positive or negative
- Latency - how long after onset
- Amplitude
- Topographic distribution

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7
Q

what is an open brain EEG

A
  • recording electro-encephalographic signals directly from the surgically exposed cerebral cortex.
    • It detects intraoperatively the cortical regions with substantial epileptiform interictal discharges. Often used simultaneously with cognitive testing.
    • Promising technique as implants for use of brain-computer interfaces (direct neural interfaces that provide control of prosthetic, electronic, or communication devices via direct use of the individual’s brain signals).
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8
Q

describe Magneto-encephalo-graphy (MEG)

A
  • a functional neuroimaging technique for mapping brain activity by recording magnetic fields
    MEG outperforms EEG with respect to spatial resolution
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9
Q

strengths of ERPs and ERFs

A
  • high temporal resolution
    Direct measure of neural activity
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10
Q

weaknesses of ERPs and ERFs

A
  • Measures only a part of neural activity
    • Poor spatial resolution
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