QM Module 4 Flashcards
Controls
a specimen who’s composition is known
Tested like patient samples to monitor performance of chemical reagents
Quantitative analysis controls
Numerical value that must fall within an expected range - checks accuracy & precision of the reagents and individual technique
Qualitative controls
Provide positive or negative results
Can results on control samples outside of acceptable range require corrective action
No, they require corrective action before patient results can be reported
What kind of errors can controls not catch/monitor
Pre-analytical errors- Incorrect specimen collection, handlingor labeling and data reporting
What is a pooled control
A bench of samples from different people put together
Advantages of pooled controls
Inexpensive, all human
Disadvantages of pooled controls
Unstable, infection precautions must be applied, may lack needed constituents, concentrations are unknown
Advantages of manufactured controls
Stable, concentrations are known, no infection precautions needed, all constituents are present
Disadvantages of manufactured controls
Expensive, not human, turbid or lipemic
Lyophilized
Freeze dried
Control material should be ___________ for an extended period of time and ___________ to yield accurate results
Control materials should be stable for an extended period of time and reproducible to yield accurate results
What does it mean for a control to be reproducible
It reacts the same
Equilibriate
Thaw
Commercial controls
Manufactured- resembles human material
Examples - chek-stix (bayer) & KOVA-Trol (ICL Scientific)
