Blood management Flashcards

exam 1

1
Q
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Blood transfusion are given to:

A

Increase
1. CaO2 (blood carrying capacity
2. DO2 (delivery of O2)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Maximum allowable blood loss equation:

A

starting hct

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

DO2 is

A

Oxygen delivery

oxygen needs to be delivered to the tissues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

DO2 (oxygen delivery) is dependent on

A
  1. oxygen content (CaO2) of blood
  2. blood flow of tissue (CO)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

CaO2 is

A

Oxygen content

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Oxygen content (CaO2) =

A

O2 dissolved in blood + O2 carried or bound by hemoglobin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

DO2 =
(equation)

A

CaO2 x CO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

VO2 is

A

oxygen consumption

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

DO2 (what is it and equation)

A

Oxygen delivery

CaO2 x CO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Oxygen content (CaO2) equation:

A

Oxygen bound to Hgb + oxygen dissolved in blood

(1.34 x Hgb x O2 sat/100) + (0.003 x PO2)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Oxygen bound to hgb calculation

A

1.34 x Hgb x O2sat/100)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Oxygen dissolved in blood calculation

A

0.003 x PO2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Normal oxygen consumption (VO2)

A

250 mL/min or

3.5 mL/kg/min

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Mixed venous measurement reflects:

A

balance of O2 delivery (DO2) and consumption (VO2)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Normal SVO2 (mixed venous saturation)

A

65-75%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Normal PvO2

A

35-45 mmHg`

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q
A
19
Q

tachycardia and decreased SVO2 (mixed venous saturation) are suggestive of

A

anemia in the setting of intraoperative hemorrhage

20
Q

DO2 integrates

A
  1. cardiac index
  2. oxyhemoglobin saturation
  3. hgb concentration

(rather just using hgb to decide on transfusion)

21
Q

Survival in high-risk patients is associated with a DO2 greater than or equal to

A

600 mL O2/min/m2

22
Q

DO2 (oxygen delivery) calculation:

A

CO (L/min) x CaO2 (mL O2/dL)

23
Q

when calculating DO2, remember to

A

convert CO (L/min) to dL/min (end value should be O2/min)

24
Q

ASA task force concludes that transfusion is usually unecessary for hgb

A

hgb>10

25
Q

ASA task force conlucdes that transfusion is usually necessary for hgb

A

hgb<6

26
Q

1 united of blood = (hgb)

A

1 unit blood = increase hgb by 1

27
Q

PRBC administration: blood loss ratio

A

1:1 or 1:2 PRBCs: mL blood loss

28
Q

One unit of PRBC will increase hct

A

increase hct 2-3%

29
Q

Mass transfusion is defined as:

A
  1. > =10 unites over 24 hours
  2. Loss of 50% of blood volume within 3 hours or less
30
Q

RBCs given with crystalloids and colloids issue:

A

Does not provide coagulation factors and can lead to dilutional coagulopaty of dilutional thrombocytopenia

31
Q

Banked blood is commonly anticoagulated by

A

citrate

32
Q

citrate issue

A

inhibits coagulation -> hypocalcemia,hyperglycemia (dextrose containing)

33
Q

Very rapid infusion of blood can (ionized calcium and results)

A

reduce ionized calcium –> hypocalcemia and hyperkalemia

34
Q

The lethal triad with mass transfusion

A
  1. Hypoperfusion/acidosis
  2. Hypothermia
  3. coagulopathy
35
Q

FFP contains

A

all coagulation factors

36
Q

Reversal of warfarin

A

FFP 5-8mL/kg

37
Q

Platelet transfusion is indicated for

A

platelet count less than 50,000

38
Q

Cryo contains

A
  1. factor VII
  2. con Willebrand factor
  3. fibrinogen (highest concentration)
39
Q

Universsal RBC donor

A

O negative

40
Q

Universal Plasma donor

A

AB positive

41
Q

Universial RBC recipient

A

AB positive

42
Q

Universal plasma recipient

A

O negative

43
Q

know blood group antigen, antibody, compatability

A

apex

44
Q

Order of prevalence of viral diseases in. banked blood

A

cytomegalovirus > hepatitis B > Hepatitis C > HIV