Dermatology - Inflammatory Blistering Diseases

Question 1

Disease defined by small blisters on face, especially lips

Answer 1

HSV1

Question 2

Disease definece by small blisters on genital area

Answer 2

HSV2

Question 3

Disease defined by multiple successive eruptions of erythmetous vesicles 2-3 mm in size, more prominent on trunk. The lesions rapidly become pustules and crust.

Accompanied by fever, chills, headache, malaise, dry cough

Answer 3

Herpes Varicella (checkenpox)

Zoster Virus

Question 4

Dew drop on a rose pedal

Answer 4

Varicella

Question 5

What disease is defined by a vesicular eruption in a dermatomal distribution (follows a nerve)?

Painful along nerve prior to development of rash

Answer 5

Herpes Zoster (Shingles)

Question 6

Disease that starts out as a single red macule or papule that quickly becomes a vesicle, the vesicle erupts and the liquid forms a honey/gold colored crust, may or may not be pruritic

Answer 6

Nonbullous Impetigo

Question 7

Disease that is defined by multiple blisters (bullae) occurring in the axillary, groin, or fold areas. The vesicles rapidly progress in to large flaccid bullae with sharp margins and no surrounding erythema. When they rupture a gold/yellow crust forms.

Answer 7

Bullous Impetigo

Question 8

Disease defined by red dermatitis surrounded by satellite micro pustules. Commonly found on mucous membranes or in skin folds

Answer 8

Fungal infections

Question 9

Disease forming tense bullae on normal or erythematous skin in elderly.

Answer 9

Bullous Pepigoid

Autoimmune disorder (IgG response at basement membrane)

Question 10

Disease defined by clusters of erytmematous papules, excoriations and vesicles. Usually happens after the pt has eaten gluten and is sensitive to it. Pruritic and symmetrically distributed, usually in pts age 20-40

Answer 10

Dermatitis Herpetiformis

Autoimmune condition

Question 11

Disease defined by predominantly flaccid blisters located on head, trunk, and intertiginous areas, usually in pts 40-60 years old

Answer 11

Pemphigus Vulgaris

Autoimmune Disorder

Associated with Nikolsky Sign

Question 12

Nikolsky Sign

Answer 12

Associated with Pemphigus Vulgaris

Slight rubbing of the skin results in exfoliation of the outermost layer forming a blister within minutes

Question 13

Disease characterized by blistering of skin on sun-exposed areas especially hands and forearms, occasionally the face. May exhibit hypertrichosis of the forehead and cheeks, skin hyper pigmentation and urine discoloration

Answer 13

Porphyria Cutanea Tarda

Deficiency in heme-syntheszing enzyme

Risk factors include Hep C, Hemochromatosis and alcoholism