Surgical Disease of the Oesophagus Flashcards

1
Q

What feature of the oesophagus protects against damage by abrasion?

A

Tough lining of stratified squamous epithelium (mucosa)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What allows effective peristalsis to move food/liquids to the stomach and keep the oesophageal lumen empty?

A

two well developed coats of skeletal muscle (tunica muscularis) that spiral and cross each other in the oesophageal wall

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What property of the oesophagus allows marked distension of the oesophagus when swallowing large food boluses?

A

longitudinal folds in the collapsed empty state

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What feature of the oesophagus allows the entry and exit respectively of food and liquids and limit the presence of food/liquid within the oesophagus to a short duration of time after swallowing?

A

The upper and lower oesophageal sphincters

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

The structure of the oesophagus is different in the cat and dog.
Is this statement true or false?

A

True
The canine oesophagus has skeletal muscle throughout its length whilst the terminal few centimetres of the feline oesophagus has smooth muscle within the tunica muscularis.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the primary pathophysiological mechanisms of disease of the oesophagus? (4)

A
  • Inflammation
  • Dysmotility
  • Obstruction - intraluminal, mural, extramural
  • Traumatic injury
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Name the pathophysiological mechanism for chronic regurgitation/ingestion of caustic or hot substance?

A

Inflammation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Name the pathophysiological mechanism for megaoesophagus.

A

Dysmotility

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Name the pathophysiological mechanism for Oesophaeal FB?

A

Intraluminal obstruct

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Name the pathophysiological mechanism for oesophgeal stricture?

A

Mural obstruct

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Name the pathophysiological mechanism for vascular ring anomaly

A

Extramural obstruct

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Name the pathophysiological mechanism for stick injury/cervical dog bite wound

A

Traumatic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Main 2 clinical signs of oesophageal disease?

A

Regurgitation
Dysphagia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Common but not main signs of oesophageal dx?

A

Cough
Dyspnea
Ptaylism
Fever
Lower appetite

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Pathogenesis of nasal discharge with oesophageal dx?

A

Aspiration of food contents into the nasopharynx and/or trachea is common in patients with frequent regurgitation –> Inflammatory rhinitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Pathogenesis of pneumonia with oesophageal dx?

A

Aspiration of food contents into the nasopharynx and/or trachea is common in patients with frequent regurgitation –> Aspiration pneumonitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

How to possible investigations into oesophageal disease? (8)

A
  • History and CE
  • Haematology + biochem
  • Fluroscopy barium swallow
  • Plain cervical xrays
  • Thoracic xrays
  • +ve contrast studies
  • CT
  • Oesophagoscopy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Which reflex will you assess to check if a patient is able to swallow?

A

Gag relfex

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

How to perform gag reflex?

A

Open patient’s mouth, touch patient’s larynx/tongue base.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Which cranial nerves does the gag reflex access?

A

Cranial nerves 9 and 10

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Other than haem/biochem, what specific blood tests could be performed to investigate the oesophaus?

A

Ach antibodies - Myasthenia Gravis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What are the challenges of Fluroscopy? (3)

A
  • Staff must be present within the room during radiation exposure to restrain the patient and to keep the fluoroscopy beam focussed on the patient, therefore there is a risk of radiation hazard to staff;
  • The study is dependent on the patient eating and being co-operative;
  • The patient is conscious, and the study is dependent on the patient remaining reasonably still.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Reasons the oesophagus has higher rates of complications historically. (4)

A
  • does not have a serosa;
  • has a segmental blood supply;
  • has no omentum;
  • is in constant motion due to swallowing and breathing.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Why may a serosal layer play a role in healing?

A

The serosa allows formation of an early fibrin seal by providing a source of pluripotent stem cells therefore may be important

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Which area of the oesophagus has no layer equivalent to the serosa and therefore possibly effect healing?

A

Cervical

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

What overlays the thoracic oesophagus which is thought to act like the serosa?

A

Mesothelium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Experimentally, how necessary has the serosa been shown to be for visceral healing?

A

Unnecessary

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

What has latest data shown the blood supply of the oesophagus to be like?

A

It is now thought that disrupted oesophageal healing is more likely to arise if the intramural blood vessels are disrupted rather than the segmental blood supply.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

How can we solve the lack of omentum in the oesophagus region?

A

The omentum can be lengthened, tunnelled through the diaphragm and used to support thoracic oesophageal surgical wounds.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Why is constant motion a poor reason for the low healing rate in the oesophagus?

A

stomach/intestines undergo peristalsis and heal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

How many tension come about with an oesophageal wound?

A

Resect and anastomosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

How many Halstead principles are there?

A

7

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

What are Halstead’s surgical principles?

A

Strict aseptic technique
Gentle tissue handling
Meticulous haemostasis
Preservation of the blood supply
Closure with minimal tension on tissues
Anatomical closure with accurate tissue apposition
Obliteration of dead space

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

What should be done to the oesophagus before incision?

A

Suction the oesophageal lumen prior to incising the oesophagus, or immediately after incision to reduce local contamination of tissues with oesophageal contents;

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

Where should be incised on the oesophaus? (2)

A
  • Incise through healthy oesophageal tissue;
  • Choose the most advantageous approach to allow good exposure and access;
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

Which direction should an oesophageal surgical approach be?

A

Make a longitudinal oesophagotomy incision rather than a transverse incision because this is less likely to cause narrowing/stricture in healing;

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

What layer must be included when closing oeosphagus?

A

Submucosa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

How many layer closure is recommended for oeosphagus?

A

1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

Where should the knots be tied when closing oesophagus?

A

Extraluminal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

What pattern to close oesophaus?

A

A simple interrupted appositional pattern is generally recommended; a simple continuous pattern is also suitable;

42
Q

Suture material for oesophagus closure?

A

Use monofilament slowly absorbable suture material (such as polydioxanone or polyglyconate) to suture the oesophagus;

43
Q

Where should sutures be placed compared to woud edge and also how far apart?

A

Sutures should be placed 3 mm from the cut edge of the oesophagus and 2-3 mm apart;

44
Q

How can thoracic oesophagus be supported?

A

an omental flap tunnelled through the diaphragm;

45
Q

Post op meds specifically for oesophaus? (3)

A

Assume postoperative oesophagitis will occur in most patients
- H2 receptor antagonists
- and/or proton pump inhibitors
- and/or gastric prokinetics;

46
Q

What put be placed for nutrition after oesophgeal surgery? How long for? (2)

A

Place a gastrostomy or percutaneous endoscopic gastrostomy (PEG) tube to allow postoperative nutrition (for 5-10 days postoperatively) whilst resting the oesophagus and avoiding oesophageal distension by food boluses, etc;

47
Q

How much of the oesophagus can be resected?

A

3-5cm

48
Q

How to close oesophageal anastomosis?

A

Simple interrupted

49
Q

Indication for oesophageal surgery? (Pathogenesis 3) (Examples 1 each)

A
  • Relief of an oesophageal obstruction that cannot be removed by non-surgical means
    = Intraluminal: endoscopically non-retrievable oesophageal foreign bodies;
    = Intramural: resection of strictures that are refractory to balloon dilation;
    = Extraluminal: transection of vascular ring anomalies;
  • Repair on an oesophageal tear or injury
    = For example a bite wound, stick injury, following oesophageal foreign body retrieval;
  • Dysmotility
    = Cricopharyngeal achalasia.
50
Q

How to approach the oesophagus area:
- Cricopharyngeus muscle
(for treatment of cricopharyngeal achalasia)

A

Lateral cervical, incision centred over laryngeal region

51
Q

How to approach the oesophagus area:
Most proximal oesophagus
(e.g. oesophageal stick injury)

A

Lateral cervical, incision centred over laryngeal region

52
Q

How to approach the oesophagus area:
Cervical oesophagus

A

Ventral midline neck, separate the sternohyoid muscles and retract the trachea to the right

53
Q

How to approach the oesophagus area:
Oesophagus at thoracic inlet/cranial thorax

A

Caudal ventral midline neck and cranial sternotomy

54
Q

How to approach the oesophagus area:
Left cranial thoracic oesophagus

A

Left 3rd or 4th intercostal thoracotomy

55
Q

How to approach the oesophagus area:
Right cranial thoracic oesophagus

A

Right 3rd, 4th or 5th intercostal thoracotomy

56
Q

How to approach the oesophagus area:
Caudal oesophagus

A

Left 7th, 8th or 9th intercostal thoracotomy

57
Q

How to approach the oesophagus area:
Caudal oesophagus and stomach

A

Combined ventral midline celiotomy and diaphragmatic incision or caudal sternotomy

58
Q

What needs to be retracted to access oesophagus via aleft 3rd/4th intercostal thoracotomy? (2)

A

Retract the brachiocephalic trunk and subclavian vessels ventrally.

59
Q

During a Left 7th, 8th or 9th intercostal thoracotomy to approach the caudal oesophagus. What anatomy must be aware of? (2)

A
  • Dorsal branches of the left and right vagus nerve run along the side of the oesophagus and join to form the dorsal vagal trunk (which runs along the dorsal oesophagus).
  • The ventral branches of the left and right vagus nerve run along the side of the oesophagus and join to form the ventral vagal trunk that runs along the ventral oesophagus.
60
Q

How to position patient the best to access midline of oesophagus?

A
  • Placing a sandbag under the neck in dorsal brings the vital anatomy nearer to the surface.
  • Having the head as straight as possible, or even taping the head to the table, helps maintain the procedure at midline.
61
Q

Which suture material for the oesophagus? (2)

A

Polyglyconate
Polydioxanone

(polyglecarprone looses tensile strength too quickly)

62
Q

The commonest locations for foreign bodies to become lodged are? (3)

A
  • Thoracic inlet
  • Heart base
  • Caudal oesophagus near diaphragm
63
Q

What makes specific areas of the oesophagus more likely to have a FB?

A

Extraoesophageal structures limit oesophageal dilation at these locations making foreign body entrapment more likely.

64
Q

Most common dog breed for oesophageal FB?

A

Small breed esp terriers

65
Q

Which bone is most likely to get stuck?

A

Vertebra. The transverse processes on these bones can “dig” into the oesophagus which can make retrieval more difficult.

66
Q

Clinical signs of an oesophageal FB? (6)

A

Retching, gagging, salivation, vocalisation, restlessness. Water and liquids can usually be swallowed and will pass the obstruction but solid food, if eaten, will be regurgitated immediately.

67
Q

Cats with oesophageal foreign bodies present quite differently to dogs. Is this statement true or false?

A

True

68
Q

Which of the following radiographic findings would suggest that there could be an oesophageal perforation or tear? (4)

A

Pneumomediastinum
Pleural effusion
Mediastinitis
Pneumothorax

69
Q

After oesophageal FB removal, what should be performed?

A

Oesophagus should be re-examined endoscopically to assess the severity of damage and a lateral thoracic radiograph should be taken to assess for pneumomediastinum and/or pneumothorax that would indicate oesophageal perforation or tearing

70
Q

How can you manage Perforations identified by a pneumomediastinum seen on post-retrieval radiographs?

A

Conservatively:
nil per os for 2-5 days. Consider placement of a gastrostomy or PEG tube, antibiotics, treatment of oesophagitis and analgesia.

71
Q

When is surgery required for the oesophagus following FB? (4)

A
  • There are radiographic signs of oesophageal perforation at the time of diagnosis
  • Endoscopic retrieval of the foreign body has failed
  • An oesophageal tear is seen on oesophagoscopy following foreign body retrieval
  • There are radiographic signs of oesophageal perforation following endoscopic foreign body retrieval.
72
Q

If we exclude lacerations secondary to oesophageal foreign bodies which have voluntarily been swallowed most other oesophageal injuries involve the A) oesophagus (rather than the B) oesophagus) so the anaesthetic and surgical approach is easier.

A

A) Cervical
B) Thoracic

73
Q

What is Cricopharyngeal achalasia?

A

upper oesophageal sphincter fails to relax during the cricopharyngeal phase of swallowing. This prevents boluses of food passing from the oropharynx into the oesophagus.

74
Q

How common is Cricopharyngeal achalasia?

A

Rare

75
Q

What age of dogs suffer Cricopharyngeal achalasia?

A

Young

76
Q

Which breed of dog suffers Cricopharyngeal achalasia?

A

Spaniel

77
Q

How do does with Cricopharyngeal achalasia present?

A

Dogs with this condition make repeated attempts to swallow when eating. This causes marked distress and discomfort and is often accompanied by gagging, coughing, dropping food from the mouth, salivation, and nasal reflux of food. Often affected dogs may be underweight but are really hungry.

78
Q

How is cricopharyngeal achalasia diagnosed?

A

after ruling out other causes of dysphagia and identifying failure of the food bolus to pass into the oesophagus during the cricopharyngeal phase of swallowing on a fluoroscopic barium swallow study.

79
Q

What must be assessed when diagnosing cricopharyngeal achalasia and why?

A

oesophageal motility is assessed in dogs with cricopharyngeal achalasia because any oesophageal motility will be unaffected by treatment of cricopharyngeal achalasia.

80
Q

What must Cricopharyngeal achalasia be differentiated from?

A

pharyngeal dysphagia

81
Q

What is pharyngeal dysphagia caused by?

A

weakness of the pharyngeal constrictor muscles

82
Q

How is cricopharyngeal achalasia treated?

A

excision of one half of the cricopharyngeus muscle

83
Q

How do you approach surgery of cricopharyngeal achalasia?

A

A lateral approach is made to the larynx and the cricopharyngeus muscle is identified overlying the cricoid cartilage.

84
Q

How is the surgery for cricopharyngeal achalasia performed?

A

The cricopharyngeus muscle is transected ventrally and then it is carefully dissected free from the oesophagus towards the dorsal midline where it is cut to remove approximately half of the muscle (i.e. the lateral portion of muscle). The wound is closed routinely.

85
Q

How soon are results seen after surgery for cricopharyngeal achalasia?

A

Immediately

85
Q

What is a vascular ring anomaly?

A

congenital malformation of the great vessels and their branches causes a constriction around the oesophagus. This acts as an extraluminal oesophageal obstruction and limits oesophageal dilation at the level of the vascular ring

85
Q

Following surgery for cricopharyngeal achalasia; What can develop after surgery because of perioperative inflammation and occasionally dogs will have recurrence of clinical signs due to fibrosis;

A

pharyngeal dysfunction

86
Q

What vascular ring anomaly makes up for 95% of cases?

A

4th aortic arch

87
Q

What does the ductus arteriosus become at birth?

A

ligamentum arteriosus

88
Q

Which side of the heart does the aorta, ductus arteriosus and pulmonary artery develop on?

A

LHS

89
Q

How does persistent aortic arch present?

A

Onset of regurgitation when the animal is weaned onto semi-solid or solid food.

90
Q

What do plain radiographs show with persistent aortic arch?

A

dilation of the oesophagus cranial to the heart base. Changes consistent with aspiration pneumonia are often present

91
Q

What will a fluoroscopic barium swallow study demonstrate with Vasc ring anomaly?

A

Abrupt and extreme narrowing of the oesophagus at the heart base with passage of only small amount of liquid barium into a normal caudal oesophagus.

92
Q

What does oesophagoscopy show with vascular ring anomaly?

A

acute oesophageal narrowing, through which the endoscope is unlikely to pass, at the heart base.

93
Q

Prior to surgical correction of a vascular ring anomaly, what needs to be corrected? (2)

A

managed medically initially to improve their nutritional status and reduce oesophagitis secondary to regurgitation.

94
Q

What are the feeding requirements for patients with a vascular ring anomaly prior to surgery? (3)

A

Feed small frequent meals of soft/liquid food.

The food bowl should be elevated such that the dog is standing up their back legs and the thoracic oesophagus is approximately vertical so that gravity can assist liquid passage through the construction.

For extremely debilitated patients a gastrostomy tube can be surgically placed, and the patient be fed exclusively by this route to improve their body condition prior to surgery.

95
Q

What is oesophagititis due to with a vascular ring anomaly?

A

Oesophagitis in these cases is due to retention of food cranial to the heart base.

96
Q

Why is referral recommended for vascular ring anomaly? (4)

A

The vascular ring is accessed via thoracotomy which provides challenges for anaesthesia and postoperative recovery;

Most surgeons will have limited experience of thoracic surgery and no experience of surgical treatment of a vascular ring anomaly;

The surgeon should be able to recognise and manage a range of vascular anomalies that might not have been clearly determined on preoperative investigations;

Failure to address all vascular anomalies or to dissect any fibrous bands that have developed around the oesophagus at the site of the vascular ring due to scarring will result in continued oesophageal constriction and persistent clinical signs with progression of oesophageal distension and dysmotility.

97
Q

Why may oesophageal resection be needed?

A
  • Neoplasia
  • Severe circumferential damage
98
Q

How much of the oesophagus can be resected?

A

3-5cm

99
Q

What can be performed during oesophagus resection to reduce tension?

A

partial myotomy

100
Q

How is a parital myotomy of the oesophagus performed?

A

The outer layer of oesophageal muscle is incised 2-3 cm proximal or distal (or both) to the anastomosis leaving the inner muscle later intact. The myotomy can heal by second intention.