15) Lymphocytes & non-malignant lymphocyte disorders Flashcards
(46 cards)
differentiation of stem cell → lymphocyte
- stem cell
- CLP
- lymphoblast
- prolymphocyte
- mature lympocyte
15% of all lymphs
NK cells
large lymph with pale cytoplasm and red granules
NK cell
2 phases of lymphopoiesis
antigen independent (in primary lymph tissue)
antigen dependent (in secondary lymph tissue)
makes immunocompetent lymphs
antigen independent lymphopoiesis
very dark blue blast
lymphoblast
large, distinct nucleoli
cytoplasm getting lighter blue
prolymphocyte
extremely variable cells
lymphs
nucleoli in mature lymphs may be seen in…
CSF
body fluids
sky blue cytoplasm
lymphs
may have countable granules, or rare vacuoles
lymphs
cytoplasm scalloped around RBCs
blue edges
reactive lymph
reactive lymph may be a precursor to…
immunoblast
huge lymph with fine chromatin and prominent nucleoli
immunoblast
salami nucleus
immunoblast
immunoblasts are found in…
secondary lymph tissues
B cells + antigen → ———– → ———–
plasmacytoid cells
plasma cells
eccentric nucleus with paranuclear unstained area
plasma cell
null cells
NK cells
function of NK cells
kill tumor cells, virally infected cells, cells coated with IgG
plasma cells with reddish-purple cytoplasm
contain more Ig than usual
flame cells
flame cells seen in….
MM
grape cells
plasma cells filled with dark globules
Mott cells
Russell bodies are found in ——— cells
Mott
(grape)
