1.5. Oesophageal Disease - Hypertensive (Nutcracker) Oesophagus Flashcards

1
Q

What causes a Hypertensive Oesophagus?

A

This can be a continuation of Gastro-Oesophageal Reflux Disease

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2
Q

Is this disease more common in Males or Females?

A

Females

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3
Q

What is the Pathology of the Disease?

A

A Hypermotile Oesophagus results in Damage to the Myenteric Nerve Plexus, which causes an increase in Lower Oesophageal Pressure

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4
Q

What are the Clinical Signs of a Hypertensive Oesophagus?

A
  1. Weight Loss / Anorexia
  2. High Pressure in the Distal Oesophagus
  3. No Aperistalsis (Achalasia)
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5
Q

Why does Weight Loss / Anorexia occur?

A

Due to the problem getting food into the Stomach

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6
Q

Why might Aspiration Pneumonia occur?

A

Due to the backup of foodstuff in the Oesophagus potentially entering into the lungs

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7
Q

What does “No Aperistalsis (Achalasia)” refer to?

A

There are still Peristaltic Waves present, unlike in Achalasia

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8
Q

What symptoms would a patient with a Hypertensive present with?

A
  1. Odynophagia
  2. Chest Pain
  3. Heartburn
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9
Q

Why would the patient present with Odynophagia / Chest Pain?

A

Due to the increase in pressure within the Oesophagus

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10
Q

Why might the patient present with heartburn?

A

Due to the potentially underlying condition of GORD

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11
Q

What investigations are necessary in a Hypertensive Oesophagus?

A
  1. Upper G.I. Endoscopy
  2. Manometry
  3. A Barium Swallow
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12
Q

What is the function of the Upper G.I. Endoscopy?

A

To visualize the Oesophagus, ensuring there are no abnormal Growths

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13
Q

What is the function of the Manometry?

A

To measure the Pressure in the Distal Oesophagus

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14
Q

What is the function of the Barium Swallow?

A

To see the if there is any obstruction - this is outdated by Endoscopy

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15
Q

What shape would be seen in a Barium Swallow for someone with a Hypertensive (Nutcracker) Oesophagus?

A

A Corkscrew shape

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16
Q

What is the Treatment of a Hypertensive (Nutcracker) Oesophagus?

A
  1. Nitrates
  2. Calcium Channel Blockers
  3. Anti-Depressants
17
Q

What are the Method of Action of the Nitrates / Calcium Channel Blockers

A

These cause the Relaxation of the Smooth Muscle around the Distal Oesophageal Sphincter

18
Q

What is the purpose of the Anti-Depressants?

A

To act as pain killers

19
Q

Is this disease progressive?

A

No