HF BBs Flashcards
What is the brand name of bisoprolol?
Zebeta
What is the initial dose of bisoprolol?
1.25 mg daily
What is the target dose of bisoprolol?
10 mg daily
What is the brand name of carvedilol?
Coreg, Coreg CR
What is the initial dose of coreg?
3.125 mg BID for two weeks
What is the target dose of coreg?
- <85 kg: 25 mg BID
- > 85 kg: 50 mg BID
What is the initial dose of coreg CR?
10 mg daily for two weeks
What is the target dose of coreg CR?
80 mg daily
What is the brand name of metoprolol CR/XL?
Toprol XL
What is the initial dose of metoprolol CR/XL?
12.5-25 mg daily
What is the target dose of metoprolol CR/XL?
200 mg daily
What is the dosing titration of BBs?
- Double dose q2weeks and MONITOR closely vital s/sxs
- Planned dose increases can be slowed if necessary to manage
- AIM FOR TARGET DOSE in 8-12 wks or highest tolerated dose
What is the dose conversion between carvedilol and coreg CR?
- 3.125 mg BID = 10 mg QD
- 6.25 mg BID = 20 mg QD
- 12.5 mg BID = 50 mg QD
- 25 mg BID = 80 mg QD
What are the monitoring parameters of BBs?
- BP (and sx hypotension), HR (1-2 wks)
- Edema and fluid retention (1-2 wks)
- Fatigue or weakness
What are the specifics to BP, sx hypotension, and HR monitoring of BB?
- Sx hypotension, bradycardia, and dizziness are uncommon if slow titration (reduce dose 50% if necessary)
- If hypotension only, reduce other drugs first
