Quiz 2 Flashcards

1
Q

plasma membrane structure and function

A

structure: lipid bilayer
function: physical barrier, gateway for exchange, communication, and site of attachment

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2
Q

transcellular

A

transport that goes THROUGH the membrane

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3
Q

paracellular

A

transport that goes PARALLEL to the membrane

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4
Q

passive transport

A

materials move down gradient, no energy is required

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5
Q

active transport

A

materials move against gradient, requires energy (ATP)

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6
Q

What are the four types of passive flux?

A

simple diffusion
osmosis
facilitated diffusion
bulk filtration

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7
Q

simple diffusion

A

passive and random motion of molecules in solution
moving from high to low concentration
rapid over short distances
directly related to temp
indirectly related to molecular size and fluid viscocity

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8
Q

osmosis

A

diffusion of water across a selectively permeable membrane
high solute conc.= low H2O conc.
cells with high solute conc. have high osmotic pressures

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9
Q

isotonic solution

A

conc. of solute outside cell=conc inside the cell

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10
Q

hypertonic solution

A

conc. of solute outside cell>conc. inside the cell
water flows out (cell shrinks)

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11
Q

hypotonic solution

A

conc. of solute outside cell<conc. inside the cell
water flows in (cell swells)

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12
Q

aquaporins

A

membrane-transport proteins providing a facilitated pathway for water flow through the membrane

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13
Q

facilitated diffusion

A

“easier diffusion”
movement from high to low conc. through a protein

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14
Q

bulk filtration

A

concentrated movement of large groups of molecules (often including water)
everything moves in the same direction
often occurs in response to pressure

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15
Q

Fick’s law (equation)

A

Jnet=-Ds(dCs/dx)
- jnet= flu
- Ds= diffusion coefficient
- dCs/dx= concentration gradient of solute

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16
Q

Fick’s Law says…

A

flux is PROPORTIONAL to temp, concentration gradient, area, and membrane permeability
flux is INVERSELY proportional to friction, molecule size, fluid viscosity, and membrane thickness

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17
Q

Types of Transporters

A

ion channel
carriers
pumps

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18
Q

Ion channels

A

membrane proteins that, when open, act as a passive conduit for ions through the membrane
cycle between open and closed conformations

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19
Q

Ion channels gated by…

A

leaky
ligand
mechanical “pull”
voltage
some are sensitive to temp-how we detect hot/cold

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20
Q

leaky gated

A

channel randomly opens/closes

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21
Q

ligand gated

A

chemical stimulus opens the channel

22
Q

mechanically gated

A

mechanical stimulus opens the channel

23
Q

voltage

A

change in membrane potential opens the channel

24
Q

Carriers/transporters

A

transport of solutes across a cell membrane
can facilitate active/passive transport

25
Q

mechanistic theme for carriers

A

conformational changes

26
Q

alternating access model

A

carriers cycle between multiple conformations in which a solute binding site is accessible on one side of the membrane or the other
never an open channel all the way through membrane

27
Q

occlusion state

A

state where the solute may not access either the inside or the outside

28
Q

Pumps

A

movement of molecules against concentration gradient

29
Q

Primary Active transport

A

directly requires ATP
movement of one (or more) solutes AGAINST their gradient using chemical energy (ATP)

30
Q

Secondary Active transport

A

utilizes energy stored in pre-existing conc. gradients
movement of one or more solutes down their conc. gradients provides the energy for the movement of other solutes AGAINST their conc. gradients

31
Q

uniport

A

movement of 1 thing in 1 direction

32
Q

symport

A

movement of 2+ things in the same direction

33
Q

antiport

A

movement of 2+ things in different directions

34
Q

Epithelial tissue

A

appears on surfaces
involved in exchange, transport, movement/clearing, protection, secretion, and sensation

35
Q

two types of secretion

A

duct (exocrine)- outside body
ductless (endocrine)- inside body

36
Q

merocrine

A

secretory products secreted by vesicular exocytosis
most common form, often continuous
ex. sweat and saliva

37
Q

apocrine

A

partial cellular breakdown (fragmentation)
cytoplasm and vesicular contents secreted
ex. milk and underarm sweat

38
Q

holocrine

A

entire cell lost with secretion
stem cells divide to replace lost cells
ex. oil glads

39
Q

types of intercellular junctions

A

tight junctions
adhering junctions
desmosomes
gap junctions

40
Q

tight junctions

A

“gatekeeper”
prevent substances from moving between cells
encircle cells near apical surface

41
Q

adhering junctions

A

actin-filament based systems
encircle cells immediately adjacent to all its neighbors
located deep to the tight junctions

42
Q

desmosomes

A

tie cells together
allow bending and twisting
do not encircle cell
provide resistance to stress

43
Q

gap junctions

A

protein channels that allow rapid communication between cells

44
Q

Connective tissue forms

A

connective tissue proper (loose and dense)
supporting connective tissue
fluid connective tissue

45
Q

connective tissue consists of…

A

specialized cells
protein fibers
ground substance

46
Q

extracellular matrix is made up of…

A

protein fibers
ground substance

47
Q

muscle tissue function

A

contract (shorten) when stimulated to create movement

48
Q

three types of muscle tissue

A

skeletal- multinucleated + striated
cardiac- striations + intercalated discs
smooth- no striations

49
Q

nervous tissue function

A

communication and control of the body

50
Q

two types of nervous tissue

A

neuron- nerve cells capable of initiating/conducting electrical activity
neuroglia (glia)- cells that support neurons