8- Gene Expression =)

Question 1

Suggest how transcription factors can reprogramme cells to form iPS cells. (2)

Answer 1

• attach to gene at promoter region
• stimulate RNA polymerase –> inhibits transcription

Question 2

Lactase persistence is caused by a mutation in DNA. This mutation does not occur in the gene coding for lactase.
Suggest and explain how this mutation causes LP. (2)

Answer 2

• mutation in promotor gene for transcription factor
• lactase gene still transcribed