ONCOFETAL ANTIGENS SPECIFIC TUMOR MARKERS

Question 1

AFP

Answer 1

Nature
- Glycoprotein
- 70kd
- 4% CHO

Cancer Type
- Hepatocellular, Germ Cell (nonseminoma)

Question 2

B - Oncofetal antigen

Answer 2

Nature
- Glycoprotein
- 80kd

Cancer Type
- Colon

Question 3

Carcinofetal ferritin

Answer 3

Nature
- Glycoprotein
- 600kd

Cancer Type
- Liver

Question 4

CEA

Answer 4

Nature
- Glycoprotein
- 22kd
- 50% CHO

Cancer Type
- Colorectal
- GIT
- Pancreatic
- Lung
- Breast

Question 5

Pancreatic oncofetal

Answer 5

Nature
- Glycoprotein
- 40kd

Cancer Type
- Pancreatic

Question 6

Squamous cell antigen

Answer 6

Nature
- Glycoprotein
- 44-48kd

Cancer Type
- Cervical
- Lung
- Skin
- head and neck (squamous)

Question 7

Tennessee antigen

Answer 7

Nature
- Glycoprotein
- 100kd

Cancer Type
- Colon
- GIT
- Bladder

Question 8

Tissue polypeptide antigen

Answer 8

Nature
- Cytokeratins 8, 18, 19

Cancer Type
- Various (Breast, Colorectal, Ovarian, Bladder)