Lecture 4 Flashcards

1
Q

What is ATP?

A
  • cellular source of energy
  • supplied by macronutrients in the diet
  • sustains physical energy, metabolism, active transport, etc.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is a Calorie?

A

measure of heat to express the energy content of food

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the conversion of a chemistry calorie vs a food calorie?

A

1000 chemistry calries = 1 food Calorie

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the difference between calorie and Calorie?

A

calorie = chemistry
Calorie = food

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the conversion of food Calorie to kcal to KJ?

A

1 food Calorie = 1 kcal = 4.18 KJ

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the method used to estimate energy in foods?

A

Calorimetry = measurement of heat production

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is calorimetry?

A

Uses heat as an indicator of the amount fo energy stored in the chemical bonds of foods (carbon-hydrogen bonds), when these bonds are broken down, they release heat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is bomb calorimetry?

A

works according to the principles of direct calorimetry (directly measures the amount of energy stored in chemical bonds of foods)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are the steps to bomb calorimetry?

A
  1. dry and weigh sample (1g) and place in enclosed chamber (the bomb) with oxygen
  2. The sample is ignited
  3. heat that is released is absorbed by water and measured
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the heat of combustion equal to?

A

Heat of combustion (gross energy) = maximum energy during a chemical reaction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the potential errors of bomb calorimetry?

A
  • overestimates energy (we don’t digest food like a bomb calorimeter burns it)
  • doesn’t take into account the energy needed for digestion and absorption
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the physiological fuel values? (Atwater values)

A

CHO = 4
Fat = 9
Protein = 4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the formula for the physiological fuel values?

A

[Heat of combustion(gross energy) - energy lost in urine] x apparent digestibility
(a-b) x c

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the units of the factors in the formula for physiological fuel values?

A

Heat of combustion(gross energy) = kcal/g
Energy lost in urine = kcal/g
Apparent digestibility = %

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are two other names for physiological fuel values?

A

available energy
metabolizable energy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Why does fat provide more kcal/g vs CHO or protein?

A

The heat of combustion (kcal/g) describes the total energy released during a chemical reaction between a hydrocarbon and oxygen to release CO2 and H2O and heat. The chemical structure of CHO, fat and protein influences the heat of combustion for macronutrients
CHO - ratio of hydrogen to oxygen = 2:1
Protein - has nitrogen which affects gross energy measurement, however in the body, nitrogen combines with hydrogen and is eliminated as urea. This loss of hydrogen affects the heat of combustion
Lipid - lipids are less oxidized than CHO and protein, ratio of hydrogen to oxygen is much greater than 2:1, lipids have lots of hydrogen atoms available for cleavage oxidation for energy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is stearic acid?

A

used for meat, poultry, fish, milk products, grains

18
Q

What is butyric acid?

A
  • SCFA
  • produced by gut bacteria
19
Q

What are the two factors that affect the heat of combustion of fatty acids?

A
  • chain length: longer chain length releases more energy
  • degree of unsaturation: the more double bonds, the less energy released (for equivalent chain length fatty acids)
20
Q

How to use the atwater values in a practical sense?

A

Can multiply the grams of the nutrient on the nutrition label by the atwater value for that nutrient and get the kcal

21
Q

What is heat increment of feeding?

A

(HIF)
- also called thermic effect of food
- energy used for the digestion, absorption, distribution and storage of nutrients
- comprises 5-30% of daily energy usage
- used to determine net energy

22
Q

What is the formula for net energy

A

Net energy = matabolizable energy - HIF

23
Q

What is net energy?

A

Supports basal metabolism, physical activity, growth, pregnancy

24
Q

What are the four components to energy expenditure?

A
  1. basal metabolic rate (BMR) - main driving force, basic energy needs, resp blood flow etc.
  2. Thermic effect of food (same thing as HIF) - absorption, metabolism of food
  3. Physical activity energy expenditure (PAEE) - varies from person to person, energy spent using voluntary muscles
  4. thermoregulation (energy spent maintaining body temp)
25
Q

How is BMR measured?

A
  • shortly after waking
  • done in a lab
  • come to lab before and sleep
  • post-absorptive state
  • lying down
  • completely relazed
  • comfortable room temperature
  • BMR = kcal per 24 hrs
26
Q

What tissues are most reflective of the BMR?

A

Muscle and bone

27
Q

What is the formula for BMR?

A

BMR = A x [M^0.75] kcal/day
A = metabolically active tissue (fat free mass, muscle and bone), the value for humans is 70
M = body weight in kg
0.75 = constant used for all vertebrates, invertebrates and even unicellular organisms

28
Q

What are factors that can affect BMR?

A
  • Genetics (inheritance of a fast or slow metabolic rate)
  • Age (young>old because of greater muscle mass)
  • Biological sex (men>women because of greater muscle mass)
  • Exercise changes body tissue proportions
    fat tissue (20% BW, 5% metabolic activity)
    muscle (30-40% BW, 25% metabolic activity)
    brain, liver, heart and kidney (5% BW, 60% metabolic activity)
  • temperature (maintaining thermoregulation
29
Q

Can you use body fat % to calculate BMR?

A

if you measure body fat %, you can have a more accurate measure of BMR

30
Q

Heat production can be used as a measure of ___________

A

energy expenditure

31
Q

What is the general combustion equation for indirect calorimetry?

A

Fuel + O2 ->(resp) CO2 + H2O + heat

Fuel - diet (CHO, protein, fat)
heat - direct cal
O2 and CO2 - indirect cal

32
Q

What is direct calorimetry?

A

Measures the heat a person generates; total heat loss, spend 24h in the chamber, very expensive and impractical

33
Q

What is indirect calorimetry?

A

energy releasing reactions in the body depending on the use of oxygen

34
Q

What does indirect calorimetry measure in order to estimate energy requirements?

A
  • oxygen consumption (L)
  • carbon dioxide production (L)
  • urinary nitrogen loss (g)
35
Q

What can indirect calorimetry not account for?

A

anaerobic processes

36
Q

What are the advantages and disadvantages of indirect calorimetry?

A

Disadvantages: hyperventilation, hard to get an airtight seal, masks are impractical, could give flawed measurements

Advantages: useful with animals, can determine the type of substrate being oxidized

37
Q

What is the respiratory quotient?

A
  • provides information about energy expenditure and biological substrate being oxidized
  • ratio of metabolic gas exchange
38
Q

What is the formula for the respiratory quotient?

A

RQ = CO2 produced/O2 consumed

39
Q

What nutrients are the main contribution of RQ?

A

assume CHO and fat

40
Q

Why does RQ vary for macronutrients?

A

Differences in chemical composition mean that each macronutrient requires a different amount of oxygen intake in relation to CO2 produced

41
Q

How to use the table to calculate RQ?

A

For each non-protein RQ value there is a caloric value for each L of O2 consumed or CO2 produced, table tells you how much CHO and fat contribute to energy