NURS 317 Unit 3 Chapter 35 Pharm Point Questions Flashcards
The nurse carefully monitors the client receiving an anterior pituitary hormone supplement who has what comorbidity? Select all that apply.
A) Severe renal dysfunction
B) Vascular disease
C) Asthma
D) Diabetes mellitus
E) Epilepsy
B) Vascular disease
C) Asthma
E) Epilepsy
Rationale:Caution should be used with any known vascular disease, epilepsy, asthma, and with hyponatremia. There is no contraindication with diabetes mellitus, and it is completely contraindicated in clients with severe renal dysfunction.
Hypopituitarism is often manifested as a growth hormone deficiency even before any signs and symptoms develop.
A) FALSE
B) TRUE
B) TRUE
Rationale:Hypopituitarism is often seen as GH deficiency before any other signs and symptoms occur. Hypopituitarism may occur as a result of developmental abnormalities or congenital defects of the pituitary, circulatory disturbances, acute or chronic inflammation of the pituitary, and pituitary tumors.
The nurse has been caring for a client who has been receiving ganirelix. What assessment finding best suggests that the drug is having the intended effect?
A) The client has had a positive home pregnancy test.
B) The client denies pain.
C) The client denies hot flashes or labile mood.
D) The client’s stature is within 2 standard deviations of the mean.
A) The client has had a positive home pregnancy test.
Rationale:Ganirelix is given to inhibit a premature luteinizing hormone surge in women undergoing controlled ovarian stimulation as part of a fertility program. A positive pregnancy test is consequently a desired outcome. This drug is not used to treat symptoms of menopause, growth disorders, or pain
Bromocriptine is a growth hormone agonist and a dopamine agonist.
A) FALSE
B) TRUE
A) FALSE
Rationale:Bromocriptine is a growth hormone antagonist as well as a dopamine agonist.
The nurse who provides care in an endocrinology clinic is working with a client who has been receiving somatropin on a regular basis for several months. What assessment should the nurse most likely prioritize when the client presents for follow-up?
A) Measure the length and width of the client’s hands and feet.
B) Review the client’s most recent fluid balance records.
C) Measure the client’s height and weight.
D) Assess the client’s menstrual patterns
C) Measure the client’s height and weight.
Rationale:While somatropin can be administered for a variety of health problems, the usual indication is growth hormone deficiency leading to growth failure in children. Consequently, the nurse should assess the client’s height and weight. Changes in the hands and feet do not occur with growth failure, and fluid balance is unlikely to be affected. Menstrual patterns would not likely exist yet
What assessment finding would indicate the need to stop somatropin administration in a child who has taken the drug for several years?
A) The child is 12 years old.
B) The child is in high school.
C) Closure of the epiphyseal plate.
D) Height of 5 ft has been reached.
C) Closure of the epiphyseal plate.
Rationale:Somatropin is contraindicated when the epiphyseal plate closes. Height, age, or year in school would not control when to stop administration.
Which client would be most likely to benefit from the administration of tesamorelin?
A) A client who has advanced prostate cancer
B) A client with stage III breast cancer
C) A client with human immunodeficiency syndrome
D) A 9-year-old client diagnosed with precocious puberty
C) A client with human immunodeficiency syndrome
Rationale:Tesamorelin is used for the reduction of excessive abdominal fat in HIV-infected patients with lipodystrophy. It is not indicated in the treatment of cancers or precocious puberty
A client has been prescribed desmopressin nasal spray, and the nurse is educating the client about self-administration. What should the nurse teach the client?
A) “Put the head of your bed at around 45 degrees before you take your nasal spray.”
B) “After you spray, tip your head back so that you don’t lose any of the medication.”
C) “Keep both of your nostrils open while you’re administering the spray.”
D) “Put the tip of the bottle about 1.5 cm into your nostril.”
D) “Put the tip of the bottle about 1.5 cm into your nostril.”
Rationale:The client should insert the tip of the spray bottle about 1.5 cm into the nostril while sitting upright. The opposite nostril should be covered with a finger, and the client should avoid leaning back after administration
Prior to a scheduled appointment, the nurse is reviewing the health record of a new client. The client’s medication regimen includes bromocriptine mesylate. The nurse should identify what likely implication of this?
A) The client has likely been treated for prostate cancer with minimal success.
B) The client likely has ambiguous sex characteristics.
C) The client likely has a much smaller-than-average stature.
D) The client likely has larger-than-average hands, feet, and face
D) The client likely has larger-than-average hands, feet, and face
Rationale:Bromocriptine mesylate is used to treat acromegaly, which often results in abnormal growth of a client’s hands, feet, and face. This drug is not used to treat cancer, GH deficiency, or unusual sex characteristics
The nurse suspects water intoxication in a client taking desmopressin as the result of what assessment finding?
A) Nasal irritation
B) Abdominal cramps
C) Calf pain
D) Drowsiness
D) Drowsiness
Rationale:Drowsiness is an indication of water intoxication. Abdominal cramps are an adverse effect of desmopressin but are not associated with water intoxication. Nasal irritation is an adverse effect of desmopressin nasal form but is not associated with water intoxication. Calf pain is not associated with water intoxication.
A client is to receive degarelix. The nurse would anticipate administering this drug by which route?
A) Subcutaneous
B) Intravenous
C) Oral
D) Intramuscular
A) Subcutaneous
Rationale:Degarelix is administered by subcutaneous injection.
The parents of a child receiving growth hormone replacement receive a new prescription for somatropin. What will the nurse teach this family about this delivery system?
A) There is no need to rotate injection sites.
B) The drug is administered as a fine mist.
C) The site does not require cleaning with an antibacterial agent.
D) Care should be taken to not touch the needle when removing the cap.
B) The drug is administered as a fine mist.
Rationale:Somatropin is a needleless delivery system that delivers the drug through the skin using a fine mist. Because it is needleless, the nurse would not need to warn parents about touching the needle. The site of administration should still be rotated to avoid disrupting skin integrity, and the site should still be cleaned with an antibacterial agent before administering to prevent introduction of bacteria
Which agent would the nurse expect to administer as an antineoplastic agent for a client with a hormone-specific cancer?
A) Somatropin
B) Ganirelix
C) Lanreotide
D) Goserelin
D) Goserelin
Rationale:Goserelin is used as an antineoplastic agent as treatment for specific hormone-stimulated cancers. Ganirelix is used to treat infertility. Somatropin is used to treat growth hormone deficiency. Lanreotide treats acromegaly.
By what routes could the nurse administer desmopressin? Select all that apply.
A) Oral
B) Subcutaneous
C) Intranasal
D) Transdermal
E) Intravenous
A) Oral
B) Subcutaneous
C) Intranasal
E) Intravenous
Rationale:Desmopressin is available for oral, IV, subcutaneous, and nasal administration. It is not available in a transdermal formula.
A client with short bowel syndrome has been prescribed somatropin rDNA origin 0.1 mg/kg subcutaneously. The client weighs 178 lbs. How many milligrams should the nurse administer? Provide your answer to one decimal place in mg
8.1mg
Rationale:The client’s weight must be converted from pounds to kilograms by dividing it by 2.2. This provides a weight of 80.91 kg. Multiplying by 0.1 mg/kg gives a dose of 8.091 mg, or 8.1 mg to one decimal place.
