Drug Cards- Benzodiazepine

Question 1

Midazolam (Versed)

Class
MOA

Answer 1

Class: Benzodiazepine
MOA: Hypnotic, sedative,GABA agonist

Question 2

Midazolam (Versed)

Indications (2)

Answer 2

-premedication before cardioversion
-acute anxiety states

Question 3

Midazolam (Versed)

Contraindications (3)

Answer 3

-hypersensitivity
-shock

Question 4

Midazolam (Versed)

Adverse Reactions (7)

Answer 4

-respiratory depression more common than in other benzodiazepines
-drowsiness
-amnesia
-respiratory depression and nausea

Question 5

Midazolam (Versed)

Drug Interactions

Answer 5

Motherwort can potentiate its effects and may result in coma

Question 6

Midazolam (Versed)

IV Dose

Answer 6

Adult: 1.0-2.5mg

Ped: 0.03mg/kg

Question 7

Midazolam (Versed)

Onset
Peak
Duration

Answer 7

Onset: Immediate
Peak: 3-5min
Duration: less than 2 hours

Question 8

Lorazepam (Ativan)

Class
MOA

Answer 8

Class: Benzodiazepine
MOA: Anticonvulsant, Sedative

Question 9

Lorazepam (Ativan)

Indications (4)

Answer 9

-major motor seizures
-status epilepticus
-premedication before cardioversion
-acute anxiety states

Question 10

Lorazepram (Ativan)

Contraindications (1)

Answer 10

-hypersensitivity

Question 11

Lorazepam (Ativan)

Adverse Reactions (9)

Answer 11

-dizziness
-drowsiness
-CNS depression
-headache
-sedation
-respiratory depression
-apnea
-hypotension
-bradycardia

Question 12

Lorazepam (Ativan)

IV Dose

Answer 12

Adult: Anxiety- 0.01-0.04mg/kg (max single 4mg)
Chemical Restraint- 2mg

Ped: Seizures- 0.1mg/kg
Restraint- 0.05mg/kg (max 2mg)

Question 13

Lorazepam (Ativan)

Onset
Peak
Duration

Answer 13

Onset: 2-5min IV
15-30min IM

Peak: less than 15min IV
2-3hours IM

Duration: 6-8hours

Question 14

Lorazepam (Ativan)

IM Dose

Answer 14

Adult: 4mg

Ped: 0.05mg/kg